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Maria Stefania De Propris Selected Research

venetoclax

1/2023High rate of durable responses with undetectable minimal residual disease with front-line venetoclax and rituximab in young, fit patients with chronic lymphocytic leukemia and an adverse biological profile: results of the GIMEMA phase II LLC1518 - VERITAS study.

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Maria Stefania De Propris Research Topics

Disease

14B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2023 - 09/2002
10Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2023 - 01/2006
5Disease Progression
04/2023 - 08/2003
4Neoplasms (Cancer)
04/2023 - 04/2011
4BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2011 - 08/2009
3Lymphoma (Lymphomas)
01/2023 - 03/2012
3Residual Neoplasm
01/2023 - 01/2019
3Philadelphia Chromosome
01/2023 - 04/2011
2Leukemia
01/2024 - 04/2011
2Acute Promyelocytic Leukemia
11/2014 - 12/2008
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2012 - 10/2011
2Blast Crisis (Blast Phase)
06/2011 - 08/2009
2Infections
08/2003 - 09/2002
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
04/2023
1Cytokine Release Syndrome
01/2023
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2023
1Pneumonia (Pneumonitis)
01/2022
1acquired Thrombotic thrombocytopenic purpura
01/2022
1Splenomegaly
03/2014
1Hemorrhage
03/2014
1Hypersplenism (Anemia, Splenic)
03/2014
1Thrombosis (Thrombus)
03/2014
1Thrombocytopenia (Thrombopenia)
03/2014
1Opportunistic Infections (Opportunistic Infection)
03/2014
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2014
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
03/2012
1Hematologic Diseases (Blood Diseases)
06/2011
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
04/2011
1Spontaneous Remission
07/2009
1Pathologic Complete Response
02/2007
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
01/2006
1Bronchiolitis Obliterans Syndrome
03/2003
1Hematologic Neoplasms (Hematological Malignancy)
01/2003
1Neutropenia
09/2002

Drug/Important Bio-Agent (IBA)

7Rituximab (Mabthera)FDA Link
01/2023 - 01/2014
5ibrutinibIBA
12/2022 - 10/2020
4Imatinib Mesylate (Gleevec)FDA Link
01/2020 - 04/2011
2Chimeric Antigen ReceptorsIBA
04/2023 - 01/2023
2Phosphotransferases (Kinase)IBA
01/2021 - 04/2011
2AntigensIBA
01/2021 - 10/2011
2fludarabineIBA
11/2020 - 09/2002
2Monoclonal AntibodiesIBA
01/2014 - 06/2011
2Cytarabine (Cytosar-U)FDA LinkGeneric
01/2012 - 09/2002
2Dasatinib (BMS 354825)FDA Link
12/2011 - 08/2009
1Lysine (L-Lysine)FDA Link
01/2024
1Histones (Histone)IBA
01/2024
1MethyltransferasesIBA
01/2024
1tisagenlecleucelIBA
04/2023
1pembrolizumabIBA
01/2023
1ribonucleotide polymeraseIBA
01/2023
1pegaspargase (Oncaspar)FDA Link
01/2023
1venetoclaxIBA
01/2023
1Agammaglobulinaemia Tyrosine KinaseIBA
01/2021
1ofatumumabFDA Link
11/2020
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2020
1Drug CombinationsIBA
01/2019
1MTOR InhibitorsIBA
01/2016
1RNA (Ribonucleic Acid)IBA
01/2016
1CD34 Antigens (CD34 Antigen)IBA
11/2014
1Chlorambucil (Leukeran)FDA Link
05/2014
1AnticoagulantsIBA
03/2014
1Oxidoreductases (Dehydrogenase)IBA
03/2012
1Proteins (Proteins, Gene)FDA Link
01/2012
1NucleophosminIBA
10/2011
1Sialic Acid Binding Ig-like Lectin 3IBA
10/2011
1AntibodiesIBA
10/2011
1Therapeutic UsesIBA
10/2011
1CD19 AntigensIBA
06/2011
1Immunoglobulin Variable RegionIBA
04/2011
1Tyrosine (L-Tyrosine)FDA Link
04/2011
1Biomarkers (Surrogate Marker)IBA
01/2011
1Tyrosine Kinase InhibitorsIBA
12/2009
1bcr-abl Fusion ProteinsIBA
12/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2009
1Interleukin-4 (Interleukin 4)IBA
07/2009
1Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2008
1Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
12/2008
1Immunoglobulin M (IgM)IBA
08/2008
1OligonucleotidesIBA
01/2006
1Anti-Bacterial Agents (Antibiotics)IBA
08/2003
1Cyclosporine (Ciclosporin)FDA LinkGeneric
03/2003
1Fluconazole (Zonal)FDA LinkGeneric
09/2002
1Trimethoprim (Proloprim)FDA LinkGeneric
09/2002
1Acyclovir (Aciclovir)FDA LinkGeneric
09/2002
1Mitoxantrone (Novantrone)FDA LinkGeneric
09/2002
1Dexamethasone (Maxidex)FDA LinkGeneric
09/2002
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
09/2002

Therapy/Procedure

5Therapeutics
04/2023 - 02/2007
2Drug Therapy (Chemotherapy)
01/2023 - 01/2020
1Cell Transplantation
01/2023
1Splenectomy
03/2014
1Transplantation
01/2012
1Salvage Therapy
01/2012
1Immunotherapy
06/2011
1Ligation
08/2008
1Stem Cell Transplantation
03/2003
1Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
03/2003
1Autologous Transplantation
01/2003
1Hematopoietic Stem Cell Mobilization
09/2002