Marek Czosnyka Selected Research

Hypocapnia

2/2024	Short-term mild hyperventilation on intracranial pressure, cerebral autoregulation, and oxygenation in acute brain injury patients: a prospective observational study.
1/2021	Analysis of Intracranial Pressure Pulse-Pressure Relationship: Experimental Validation.
5/2020	Critical closing pressure during experimental intracranial hypertension: comparison of three calculation methods.
1/2012	How does moderate hypocapnia affect cerebral autoregulation in response to changes in perfusion pressure in TBI patients?
4/2011	Effect of hyper- and hypocapnia on cerebral arterial compliance in normal subjects.

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Marek Czosnyka Research Topics

Disease

51	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2023 - 01/2003
21	Intracranial Hypertension 02/2024 - 01/2008
17	Brain Injuries (Brain Injury) 02/2024 - 02/2006
17	Hypotension (Low Blood Pressure) 01/2022 - 06/2002
13	Craniocerebral Trauma (Head Injury) 01/2016 - 08/2003
12	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 05/2022 - 08/2005
10	Hydrocephalus (Hydrocephaly) 01/2021 - 01/2002
5	Hypocapnia 02/2024 - 04/2011
5	Critical Illness (Critically Ill) 10/2023 - 10/2007
5	Heart Arrest (Cardiac Arrest) 12/2022 - 10/2011
5	Hypertension (High Blood Pressure) 10/2018 - 10/2011
4	Wounds and Injuries (Trauma) 10/2020 - 10/2007
4	Stroke (Strokes) 01/2020 - 03/2008
3	COVID-19 10/2023 - 01/2021
3	Hypercapnia 01/2021 - 04/2011
3	Hypothermia 01/2019 - 10/2011
3	Hemorrhage 11/2018 - 06/2012
3	Intracranial Vasospasm 02/2014 - 08/2005
2	Cerebrospinal Fluid Leak 04/2023 - 06/2002
2	Sepsis (Septicemia) 12/2022 - 05/2007
2	Coma (Comas) 12/2022 - 04/2015
2	Normal Pressure Hydrocephalus 11/2022 - 08/2015
2	Patent Ductus Arteriosus 01/2022 - 01/2020
2	Hypoxia (Hypoxemia) 01/2021 - 01/2020
2	Atrophy 01/2021 - 03/2020
2	Bradycardia 01/2020 - 10/2018
2	Pseudotumor Cerebri (Idiopathic Intracranial Hypertension) 02/2019 - 01/2016
2	Hyperventilation 01/2019 - 02/2006
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2018 - 08/2005
2	Persistent Vegetative State (Vegetative State) 01/2016 - 03/2015
2	Pathologic Constriction (Stenosis) 02/2014 - 01/2013
2	Infarction (Infarctions) 06/2012 - 06/2002
2	Brain Ischemia (Cerebral Ischemia) 09/2010 - 08/2007
2	Cerebral Infarction 07/2009 - 06/2002
2	Contusions 01/2009 - 11/2003
1	Clinical Deterioration 01/2024
1	AIDS-Related Complex (ARC) 10/2023
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 10/2023
1	Respiratory Insufficiency (Respiratory Failure) 01/2023
1	Meningitis 12/2022
1	Metabolic Brain Diseases (Encephalopathy, Metabolic) 12/2022
1	Seizures (Absence Seizure) 12/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Acute Kidney Injury (Acute Renal Failure) 01/2021
1	Placental Insufficiency 01/2020
1	Cross Infection (Nosocomial Infection) 11/2019
1	Ischemic Stroke 11/2019
1	Deglutition Disorders (Dysphagia) 11/2019
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2019
1	Heart Diseases (Heart Disease) 11/2018
1	Diseases Newborn Infant 11/2018
1	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 11/2018
1	Tachycardia (Tachyarrhythmias) 10/2018
1	Orthostatic Hypotension (Postural Hypotension) 12/2017

Drug/Important Bio-Agent (IBA)

45	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 09/2023 - 11/2003
9	Oxygen (Dioxygen)IBA 01/2021 - 06/2002
7	Carbon DioxideIBA 02/2024 - 01/2009
6	Adenosine Monophosphate (AMP)IBA 01/2023 - 12/2017
5	Biomarkers (Surrogate Marker)IBA 10/2023 - 02/2011
5	ElementsIBA 02/2016 - 10/2002
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2009 - 08/2005
4	Pravastatin (Pravachol)FDA LinkGeneric 12/2007 - 08/2005
3	salicylhydroxamic acid (SHAM)IBA 01/2020 - 10/2011
2	Phosphopyruvate Hydratase (Enolase)IBA 10/2023 - 01/2017
2	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 04/2004
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2021 - 04/2004
2	Ringer's LactateIBA 05/2020 - 01/2016
2	CytokinesIBA 01/2017 - 01/2017
2	Propofol (Diprivan)FDA LinkGeneric 02/2006 - 08/2003
1	CreatinineIBA 10/2023
1	Oxyhemoglobins (Oxyhemoglobin)IBA 01/2021
1	deoxyhemoglobinIBA 01/2021
1	Cytidine Triphosphate (CTP)IBA 12/2017
1	XenonIBA 12/2017
1	Vasodilator Agents (Vasodilators)IBA 09/2017

Therapy/Procedure

16	Therapeutics 09/2023 - 08/2005
12	Critical Care (Surgical Intensive Care) 01/2024 - 01/2006
12	Decompressive Craniectomy 01/2022 - 01/2008
7	Lasers (Laser) 01/2021 - 05/2009
5	Catheters 12/2018 - 04/2009
4	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 02/2024 - 01/2022
4	Resuscitation 12/2022 - 10/2011
4	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2021 - 02/2010
4	Artificial Respiration (Mechanical Ventilation) 11/2019 - 01/2008
3	Extracorporeal Membrane Oxygenation 10/2023 - 11/2018
3	Ventriculoperitoneal Shunt 01/2022 - 01/2013
2	Craniotomy 05/2022 - 01/2022
2	Ventriculostomy 08/2007 - 01/2002
1	Precision Medicine 11/2022
1	Home Nursing (Nursing, Home) 11/2022
1	Infant Equipment (Crib) 01/2022
1	Mechanical Ventilators (Ventilator) 01/2021
1	Decompression 01/2021
1	Continuous Positive Airway Pressure 01/2020
1	Thrombectomy 01/2020
1	Urinary Catheters 11/2019
1	Length of Stay 11/2019
1	Liver Transplantation 01/2019
1	Stethoscopes 01/2018
1	Controlled Hypotension 09/2017