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Vincent L Cryns Selected Research

Proteins (Proteins, Gene)

1/2019Methionine restriction activates the integrated stress response in triple-negative breast cancer cells by a GCN2- and PERK-independent mechanism.
10/2015αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis.
3/2005The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.
6/2004Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.

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Vincent L Cryns Research Topics

Disease

42Neoplasms (Cancer)
04/2024 - 06/2004
31Breast Neoplasms (Breast Cancer)
04/2024 - 02/2005
11Triple Negative Breast Neoplasms
12/2021 - 07/2010
4Neoplasm Metastasis (Metastasis)
01/2022 - 08/2011
3Type 2 Diabetes Mellitus (MODY)
01/2023 - 01/2018
3Carcinoma (Carcinomatosis)
01/2023 - 01/2006
3Alzheimer Disease (Alzheimer's Disease)
05/2006 - 08/2003
2Prostatic Neoplasms (Prostate Cancer)
11/2020 - 12/2018
2Obesity
01/2018 - 09/2016
1Autoimmune Diseases (Autoimmune Disease)
12/2023
1Immune System Diseases (Immune Disorders)
12/2023
1Mitochondrial Diseases (Mitochondrial Disease)
11/2023
1Diabetes Mellitus
12/2018
1Head and Neck Neoplasms (Head and Neck Cancer)
11/2018
1Thinness
01/2018
1Osteoporosis
09/2017
1Pleural Effusion (Pleural Effusions)
10/2016
1Weight Gain
09/2016
1Glucose Intolerance
09/2016
1Insulin Resistance
09/2016
1Melanoma (Melanoma, Malignant)
06/2015
1Brain Neoplasms (Brain Tumor)
01/2014
1Retinoblastoma (Glioblastoma, Retinal)
04/2013

Drug/Important Bio-Agent (IBA)

10Crystallins (Crystallin)IBA
09/2016 - 01/2006
7Methionine (L-Methionine)FDA Link
01/2022 - 06/2015
7Estrogen ReceptorsIBA
06/2017 - 11/2006
6CaspasesIBA
10/2020 - 08/2003
6LigandsIBA
08/2011 - 06/2004
5Phosphatidylinositols (Phosphatidylinositol)IBA
04/2024 - 01/2019
5Peptides (Polypeptides)IBA
11/2019 - 04/2010
5Progesterone Receptors (Progesterone Receptor)IBA
06/2017 - 10/2008
5Small Heat-Shock ProteinsIBA
11/2010 - 03/2005
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2008 - 06/2004
4Metformin (Glucophage)FDA LinkGeneric
01/2023 - 06/2017
4Proteins (Proteins, Gene)FDA Link
01/2019 - 06/2004
4Biomarkers (Surrogate Marker)IBA
11/2018 - 10/2008
3Monoclonal AntibodiesIBA
06/2017 - 05/2008
3Molecular Chaperones (Chaperone, Molecular)IBA
09/2016 - 01/2014
2Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
04/2024 - 09/2004
2Phosphotransferases (Kinase)IBA
04/2024 - 01/2019
2AntioxidantsIBA
12/2021 - 10/2020
2ThioredoxinsIBA
12/2021 - 10/2020
2Auranofin (Ridaura)FDA Link
12/2021 - 10/2020
2Essential Amino AcidsIBA
12/2021 - 01/2019
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021 - 10/2020
2AndrogensIBA
11/2020 - 12/2018
2Paclitaxel (Taxol)FDA LinkGeneric
11/2019 - 08/2013
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
11/2019 - 08/2011
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
11/2018 - 10/2016
2Glycogen Synthase (Synthase I)IBA
11/2018 - 10/2016
2CytokinesIBA
09/2016 - 03/2005
2Epidermal Growth Factor (EGF)IBA
10/2015 - 06/2008
2TNF-Related Apoptosis-Inducing LigandIBA
06/2015 - 08/2011
2PolymersIBA
08/2011 - 09/2010
2lexatumumabIBA
08/2011 - 05/2008
2Doxorubicin (Adriamycin)FDA LinkGeneric
08/2011 - 09/2010
2Caspase 8 (Caspase-8)IBA
08/2011 - 06/2005
2Apoptosis Regulatory ProteinsIBA
10/2008 - 02/2005
2SurvivinIBA
05/2008 - 02/2005
2Caspase 3 (Caspase-3)IBA
03/2005 - 06/2004
2alpha-Crystallin B ChainIBA
03/2005 - 10/2002
1Inositol PhosphatesIBA
04/2024
1phosphoinositide-3,4,5-triphosphateIBA
04/2024
1Environmental Pollutants (Pollutants, Environmental)IBA
12/2023
1Heme (Haem)IBA
11/2023
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
05/2023
1Tight Junction ProteinsIBA
01/2023
1OccludinIBA
01/2023
1Cadherins (E-Cadherin)IBA
01/2023
1ClaudinsIBA
01/2023
1EnzymesIBA
12/2021
1Glutathione (Reduced Glutathione)IBA
12/2021
1Thioredoxin-Disulfide ReductaseIBA
12/2021
1Hypoglycemic Agents (Hypoglycemics)IBA
11/2020
1Lysine (L-Lysine)FDA Link
10/2020
1Oxidoreductases (Dehydrogenase)IBA
10/2020
1CycloleucineIBA
05/2019
1Calcium IsotopesIBA
09/2017
1CalciumIBA
09/2017
1Irinotecan (Camptosar)FDA LinkGeneric
10/2016
1Glycogen Synthase Kinase 3IBA
10/2016
1Glucose (Dextrose)FDA LinkGeneric
09/2016
1Insulin (Novolin)FDA Link
09/2016
1Messenger RNA (mRNA)IBA
06/2015
1AntigensIBA
06/2015
1EstersIBA
04/2015
1MicellesIBA
10/2014
1Silicon Dioxide (Silica)FDA LinkGeneric
08/2013
1RutheniumIBA
08/2013
1E2F Transcription FactorsIBA
04/2013
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
11/2011
1Biotin (Vitamin H)FDA Link
08/2011
1catechol (pyrocatechol)IBA
08/2011
1Cell Surface ReceptorsIBA
08/2011
1Bortezomib (Velcade)FDA Link
08/2011
1Proteasome Endopeptidase Complex (Proteasome)IBA
08/2011
1Boronic AcidsIBA
08/2011

Therapy/Procedure

16Therapeutics
11/2020 - 02/2005
3Drug Therapy (Chemotherapy)
01/2022 - 10/2008
1Diet Therapy (Therapy, Diet)
01/2018