David H Coy Selected Research

Matrix Metalloproteinases (MMPs)

2/2007

A conjugate of camptothecin and a somatostatin analog against prostate cancer cell invasion via a possible signaling pathway involving PI3K/Akt, alphaVbeta3/alphaVbeta5 and MMP-2/-9.

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David H Coy Research Topics

Disease

26	Neoplasms (Cancer) 01/2024 - 04/2002
5	Carcinoid Tumor (Carcinoid) 01/2016 - 01/2008
4	Neuroblastoma 01/2008 - 09/2002
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2016 - 01/2012
3	Hypoglycemia (Reactive Hypoglycemia) 08/2013 - 01/2012
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2018 - 09/2005
2	Leukemia 09/2017 - 01/2008
2	Body Weight (Weight, Body) 09/2017 - 01/2004
2	Hepatocellular Carcinoma (Hepatoma) 04/2017 - 01/2015
2	Acromegaly 01/2016 - 01/2015
2	Pancreatitis 10/2011 - 01/2005
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2011 - 05/2004
2	Prostatic Neoplasms (Prostate Cancer) 01/2008 - 02/2007
2	Heart Failure 06/2002 - 01/2002
1	Multiple Sclerosis 09/2017
1	Cardiotoxicity 09/2017
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2016
1	Cushing Syndrome 01/2016
1	Polycystic liver disease 01/2015
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2015
1	Liver Diseases (Liver Disease) 01/2015
1	Acute Kidney Injury (Acute Renal Failure) 11/2013
1	Prediabetic State (Prediabetes) 08/2013
1	Epilepsy (Aura) 08/2013
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2013
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2012
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2008
1	Neoplasm Metastasis (Metastasis) 01/2008
1	Breast Neoplasms (Breast Cancer) 09/2007
1	Lung Neoplasms (Lung Cancer) 09/2006
1	Toxic Optic Neuropathy 04/2005
1	Choroidal Neovascularization 04/2005
1	Colonic Neoplasms (Colon Cancer) 05/2004
1	Bronchopulmonary Dysplasia 09/2003

Drug/Important Bio-Agent (IBA)

10	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2015 - 09/2002
8	Somatostatin Receptors (Somatostatin Receptor)IBA 01/2018 - 09/2002
8	Peptides (Polypeptides)IBA 01/2016 - 06/2002
8	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 09/2011 - 05/2004
8	CamptothecinIBA 09/2007 - 03/2003
6	BombesinIBA 09/2011 - 06/2002
5	LigandsIBA 10/2013 - 03/2003
4	JF-10-81IBA 01/2011 - 07/2004
3	Cytotoxins (Cytolysins)IBA 01/2018 - 09/2006
3	somatostatin receptor 2IBA 08/2013 - 01/2012
3	Insulin (Novolin)FDA Link 08/2013 - 01/2012
3	Glucagon (Glukagon)FDA Link 08/2013 - 01/2012
3	bombesin receptor subtype 3IBA 08/2011 - 02/2008
3	Vasoactive Intestinal Peptide Receptors (Vasoactive Intestinal Peptide Receptor)IBA 09/2007 - 01/2005
2	Histone Deacetylase InhibitorsIBA 01/2018 - 01/2015
2	Member 2 Group A Nuclear Receptor Subfamily 4IBA 04/2017 - 01/2016
2	lanreotide (Somatuline)FDA Link 01/2016 - 01/2015
2	Valproic Acid (Depakote)FDA LinkGeneric 01/2016 - 08/2013
2	Growth Hormone (Somatotropin)IBA 01/2016 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 01/2015 - 01/2012
2	Streptozocin (Streptozotocin)FDA Link 07/2013 - 01/2012
2	CorticosteroneIBA 07/2013 - 01/2012
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2012 - 09/2011
2	CytokinesIBA 10/2011 - 01/2005
2	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 10/2011 - 09/2007
2	Bombesin Receptors (Bombesin Receptor)IBA 08/2011 - 05/2004
2	Glucose (Dextrose)FDA LinkGeneric 08/2010 - 02/2008
2	BromidesIBA 09/2006 - 05/2004
2	Peptide Hormones (Polypeptide Hormones)IBA 09/2006 - 03/2003
2	TubulinIBA 05/2004 - 01/2004
2	AdrenomedullinIBA 06/2002 - 01/2002
1	Maytansine (Maitansine)IBA 01/2024
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	Androstenedione (4 Androstene 3,17 dione)IBA 09/2017
1	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 09/2017
1	Mitoxantrone (Novantrone)FDA LinkGeneric 09/2017
1	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2016
1	Octreotide (Sandostatin)FDA LinkGeneric 01/2016
1	Notch ReceptorsIBA 01/2016
1	pasireotideIBA 01/2016
1	AcidsIBA 01/2015
1	1-dodecylpyridoxal (PLD)IBA 01/2015
1	Diatrizoate Meglumine (Gastrograffin)FDA LinkGeneric 11/2013
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 08/2013
1	Hypoglycemic Agents (Hypoglycemics)IBA 07/2013
1	Blood Glucose (Blood Sugar)IBA 01/2012
1	Cyclic AMP (AMP, Cyclic)IBA 01/2012
1	Hormones (Hormone)IBA 01/2012
1	Peptide Receptors (Peptide Receptor)IBA 09/2011
1	AN 238IBA 01/2011
1	RC 121IBA 01/2011
1	Matrix Metalloproteinases (MMPs)IBA 02/2007
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 09/2006
1	ArgonIBA 04/2005
1	Secretin FDA Link 01/2005
1	CeruletideIBA 01/2005
1	Type I Vasoactive Intestinal Polypeptide ReceptorsIBA 01/2005
1	BuffersIBA 07/2004
1	CarbamatesIBA 07/2004
1	ProdrugsIBA 05/2004
1	fosbretabulin (combretastatin A4)IBA 01/2004

Therapy/Procedure

7	Therapeutics 01/2018 - 02/2007
2	Drug Therapy (Chemotherapy) 01/2012 - 01/2008
1	Injections 01/2008
1	Lasers (Laser) 04/2005
1	Intraperitoneal Injections 01/2005