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Robert H Costa Selected Research

Phenobarbital (Luminal)

1/2007A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment.
4/2004Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.
9/2003Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions.

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Robert H Costa Research Topics

Disease

17Neoplasms (Cancer)
06/2011 - 01/2003
7Hepatocellular Carcinoma (Hepatoma)
01/2007 - 01/2003
4Osteosarcoma (Osteogenic Sarcoma)
07/2008 - 04/2004
3Infections
09/2004 - 04/2002
3Adenoviridae Infections (Adenovirus Infections)
01/2003 - 01/2002
2Colorectal Neoplasms (Colorectal Cancer)
06/2010 - 04/2007
2Liver Neoplasms (Liver Cancer)
01/2007 - 06/2005
2Carcinoma (Carcinomatosis)
10/2006 - 02/2006
2Hypertrophy
06/2005 - 01/2003
2Hemorrhage
03/2004 - 06/2002
2Lung Injury
09/2003 - 06/2002
1Neoplasm Metastasis (Metastasis)
01/2011
1Colonic Neoplasms (Colon Cancer)
04/2007
1Hypertension (High Blood Pressure)
03/2007
1Breast Neoplasms (Breast Cancer)
02/2007
1Vascular System Injuries
09/2006
1Lung Neoplasms (Lung Cancer)
02/2006
1Adenocarcinoma of Lung
02/2006
1Prostatic Neoplasms (Prostate Cancer)
02/2006
1Adenocarcinoma
02/2006
1Carcinogenesis
02/2005
1Retinoblastoma (Glioblastoma, Retinal)
03/2004
1Liver Diseases (Liver Disease)
09/2003
1Starvation
06/2003
1Acute-Phase Reaction
01/2003
1Psychotic Disorders (Schizoaffective Disorder)
07/2002
1Schizophrenia (Dementia Praecox)
07/2002
1Cholestasis
06/2002
1Bile Duct Diseases (Bile Duct Disease)
06/2002
1Coinfection
04/2002

Drug/Important Bio-Agent (IBA)

17Transcription Factors (Transcription Factor)IBA
01/2011 - 04/2002
12Proteins (Proteins, Gene)FDA Link
01/2007 - 04/2002
6Small Interfering RNA (siRNA)IBA
04/2007 - 12/2005
4Messenger RNA (mRNA)IBA
09/2004 - 06/2002
3Forkhead Transcription Factors (Forkhead Box Proteins)IBA
06/2011 - 10/2006
3Peptides (Polypeptides)IBA
01/2011 - 02/2005
3Forkhead Box Protein M1IBA
07/2008 - 12/2005
3Phenobarbital (Luminal)FDA Link
01/2007 - 09/2003
3Diethylnitrosamine (N-Nitrosodiethylamine)IBA
01/2007 - 09/2003
3AgarIBA
02/2006 - 04/2004
3Glucose (Dextrose)FDA LinkGeneric
06/2003 - 01/2002
3GlycogenIBA
06/2003 - 04/2002
2Cyclin B1IBA
04/2007 - 09/2006
2Cre recombinaseIBA
04/2007 - 02/2006
2SurvivinIBA
04/2007 - 01/2007
2Complementary DNA (cDNA)IBA
04/2007 - 09/2004
2CarcinogensIBA
01/2007 - 02/2006
2CCAAT-Enhancer-Binding Protein-alphaIBA
02/2006 - 04/2002
2DNA (Deoxyribonucleic Acid)IBA
09/2005 - 01/2003
2Butylated Hydroxytoluene (BHT)IBA
09/2003 - 06/2002
1StathminIBA
01/2011
1Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
01/2011
1PlicamycinFDA Link
06/2010
1Anti-Bacterial Agents (Antibiotics)IBA
06/2010
1JNK Mitogen-Activated Protein KinasesIBA
07/2008
1Matrix Metalloproteinases (MMPs)IBA
07/2008
1Dextrans (Dextran)FDA Link
04/2007
1villinIBA
04/2007
1AzoxymethaneIBA
04/2007
1Bromodeoxyuridine (BrdU)IBA
04/2007
1Cyclin A2IBA
04/2007
1Transcription Factor 7-Like 2 ProteinIBA
04/2007
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
04/2007
1SaltsIBA
03/2007
1Factor X (Stuart Factor)IBA
02/2007
1Histones (Histone)IBA
02/2007
1Aurora Kinase BIBA
01/2007
1Polo-Like Kinase 1IBA
01/2007
1MitogensIBA
04/2006
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2006
1Cyclin D1IBA
04/2006
1Urethane (Ethyl Carbamate)IBA
02/2006
1human FOXM1 proteinIBA
02/2006
1ChromatinIBA
02/2006
1Cyclin-Dependent Kinases (cdk Proteins)IBA
12/2005
1Cyclin-Dependent Kinase Inhibitor ProteinsIBA
12/2005
1Platelet Endothelial Cell Adhesion Molecule-1IBA
06/2005
1Growth Hormone (Somatotropin)IBA
09/2004
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
03/2004
1myosin VIIBA
03/2004
1Proto-Oncogene Proteins c-metIBA
03/2004
1Nonesterified Fatty Acids (NEFA)IBA
06/2003
1Ketone BodiesIBA
06/2003
1Protein Kinases (Protein Kinase)IBA
01/2003
1Hepatocyte Nuclear Factor 3-betaIBA
01/2003
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2003
1IgA receptor (protein B)IBA
06/2002
1Surface-Active Agents (Surfactants)IBA
06/2002
1cadherin 5IBA
06/2002
1Liver GlycogenIBA
04/2002
1Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA
04/2002
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
04/2002
1BilirubinIBA
01/2002
1Bile Acids and Salts (Bile Acids)IBA
01/2002

Therapy/Procedure

3Therapeutics
02/2005 - 09/2003
1Intraperitoneal Injections
04/2007
1Hepatectomy
11/2002