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Luciano J Costa Selected Research

B-Cell Lymphoma (Lymphoma, B Cell)

10/2021Phase 2 study of venetoclax plus carfilzomib and dexamethasone in patients with relapsed/refractory multiple myeloma.
11/2017C-MYC-positive relapsed and refractory, diffuse large B-cell lymphoma: Impact of additional "hits" and outcomes with subsequent therapy.
9/2014Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.
7/2008Germinal center B (GCB) and non-GCB cell-like diffuse large B cell lymphomas have similar outcomes following autologous haematopoietic stem cell transplantation.

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Luciano J Costa Research Topics

Disease

66Multiple Myeloma
04/2024 - 05/2009
12Neoplasms (Cancer)
04/2024 - 09/2014
10Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021 - 10/2008
8Lymphoma (Lymphomas)
11/2021 - 09/2011
6Residual Neoplasm
11/2023 - 01/2020
5Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2016 - 09/2013
4Disease Progression
01/2024 - 12/2011
4B-Cell Lymphoma (Lymphoma, B Cell)
10/2021 - 07/2008
4Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
12/2017 - 02/2014
3Chromosome Aberrations (Chromosome Abnormalities)
04/2024 - 12/2021
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022 - 03/2016
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2018 - 12/2013
3Graft vs Host Disease (Graft-Versus-Host Disease)
01/2018 - 05/2009
3Hodgkin Disease (Hodgkin's Disease)
10/2015 - 08/2010
2Body Weight (Weight, Body)
12/2022 - 10/2008
2Acute Promyelocytic Leukemia
01/2022 - 01/2021
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2021 - 03/2015
2Second Primary Neoplasms (Neoplasms, Second)
01/2018 - 01/2015
2Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
10/2015 - 07/2014
2Leukemia
09/2014 - 12/2013
2Renal Cell Carcinoma (Grawitz Tumor)
12/2007 - 03/2007
1Infections
12/2023
1Immunoglobulin Light-chain Amyloidosis
11/2023
1Agammaglobulinemia (Hypogammaglobulinemia)
08/2023
1Cytokine Release Syndrome
03/2023
1Thrombosis (Thrombus)
11/2022
1Anemia
04/2022
1Autoimmune Hypothyroidism
01/2022
1Frailty
01/2022
1Carcinogenesis
12/2021
1Pathologic Complete Response
01/2021
1Paraproteinemias (Monoclonal Gammopathy)
01/2019
1Bronchiolitis Obliterans Syndrome
11/2018

Drug/Important Bio-Agent (IBA)

16Dexamethasone (Maxidex)FDA LinkGeneric
04/2024 - 11/2012
15Lenalidomide (CC 5013)FDA Link
04/2024 - 01/2015
13daratumumabIBA
04/2024 - 01/2019
10Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2023 - 08/2011
9Bortezomib (Velcade)FDA Link
04/2024 - 11/2012
8Chimeric Antigen ReceptorsIBA
12/2023 - 01/2019
7Monoclonal AntibodiesIBA
01/2024 - 03/2015
6Proteasome InhibitorsIBA
01/2024 - 01/2018
5bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA
04/2024 - 11/2021
5carfilzomibIBA
11/2023 - 04/2015
4Biomarkers (Surrogate Marker)IBA
11/2023 - 01/2020
4Proteins (Proteins, Gene)FDA Link
11/2023 - 10/2021
4B-Cell Maturation AntigenIBA
07/2023 - 01/2022
3trans-crotonin (CTN)IBA
10/2020 - 11/2018
3selinexorIBA
01/2020 - 01/2018
3Rituximab (Mabthera)FDA Link
01/2020 - 11/2014
3Sirolimus (Rapamycin)FDA Link
11/2018 - 03/2007
3Busulfan (Busulfex)FDA Link
01/2016 - 12/2013
2idecabtagene vicleucelIBA
04/2024 - 03/2023
2Adenosine Monophosphate (AMP)IBA
04/2024 - 01/2024
2Immunomodulating AgentsIBA
03/2023 - 01/2022
2Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2022 - 01/2021
2Arsenic Trioxide (Trisenox)FDA Link
01/2022 - 01/2021
2plerixaforFDA Link
01/2019 - 12/2014
2carboxyl radical (COO-)IBA
01/2019 - 01/2019
2Prednisone (Sone)FDA LinkGeneric
01/2019 - 11/2018
2Melphalan (Alkeran)FDA LinkGeneric
01/2018 - 10/2008
2Phosphatidylinositols (Phosphatidylinositol)IBA
10/2016 - 03/2007
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2014 - 02/2014
1vinyltriethoxysilane (VTES)IBA
11/2022
1Immunoglobulin A (IgA)IBA
04/2022
1Immunoglobulin G (IgG)IBA
04/2022
1Immunoglobulin IsotypesIBA
04/2022
1Cyclin D1IBA
01/2022
1Blood Group Antigens (Blood Groups)IBA
01/2022
1PENTAIBA
11/2021
1Immunologic Factors (Immunomodulators)IBA
11/2021
1venetoclaxIBA
10/2021
1Tyrosine Kinase InhibitorsIBA
01/2021
1isatuximabIBA
01/2019
1obinutuzumabIBA
01/2019
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019
1ParaproteinsIBA
01/2019
1Vincristine (Oncovin)FDA LinkGeneric
01/2019
1fludarabineIBA
11/2018
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
11/2018
1Calcineurin InhibitorsIBA
11/2018
1Cytarabine (Cytosar-U)FDA LinkGeneric
11/2018
1Oncogene Proteins (Oncogene Protein)IBA
01/2018
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2018
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
01/2018

Therapy/Procedure

50Therapeutics
04/2024 - 12/2007
19Cell Transplantation
01/2022 - 02/2013
9Stem Cell Transplantation
01/2024 - 07/2008
9Transplantation
10/2023 - 10/2008
7Drug Therapy (Chemotherapy)
12/2021 - 01/2005
6Hematopoietic Stem Cell Transplantation
01/2022 - 05/2009
4Autologous Transplantation
02/2017 - 11/2013
3Immunotherapy
04/2024 - 11/2014
3Salvage Therapy
01/2021 - 08/2011
2Withholding Treatment
11/2023 - 01/2022
2Homologous Transplantation
03/2015 - 02/2013
1Aftercare (After-Treatment)
11/2023
1Duration of Therapy
11/2023
1Hematopoietic Stem Cell Mobilization
01/2023
1Blood Component Removal (Apheresis)
01/2019
1Photopheresis
11/2018