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Brian D Cleaver Selected Research

Enzyme Replacement Therapy

6/2013Phase I/II trial of adeno-associated virus-mediated alpha-glucosidase gene therapy to the diaphragm for chronic respiratory failure in Pompe disease: initial safety and ventilatory outcomes.

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Brian D Cleaver Research Topics

Disease

2Glycogen Storage Disease Type II (Pompe's Disease)
06/2013 - 04/2011
1Neurodegenerative Diseases (Neurodegenerative Disease)
09/2023
1Canavan Disease (Leukodystrophy, Spongiform)
09/2023
1Cardiomegaly (Heart Hypertrophy)
06/2013
1Neuromuscular Diseases (Neuromuscular Disease)
06/2013
1Respiratory Insufficiency (Respiratory Failure)
06/2013
1Muscular Diseases (Myopathy)
04/2011

Drug/Important Bio-Agent (IBA)

2AcidsIBA
06/2013 - 04/2011
2alpha-Glucosidases (Acid Maltase)IBA
06/2013 - 04/2011
2GlycogenIBA
06/2013 - 04/2011
1aspartoacylaseIBA
09/2023
1EnzymesIBA
04/2011

Therapy/Procedure

2Therapeutics
09/2023 - 04/2011
1Enzyme Replacement Therapy
06/2013
1Artificial Respiration (Mechanical Ventilation)
06/2013