Alan D Cherrington Selected Research

Fructose

1/2023	A high-fat and fructose diet in dogs mirrors insulin resistance and β-cell dysfunction characteristic of impaired glucose tolerance in humans.
1/2019	Sympathetic Denervation of the Common Hepatic Artery Lessens Glucose Intolerance in the Fat- and Fructose-Fed Dog.
1/2016	Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.
5/2015	Chronic overeating impairs hepatic glucose uptake and disposition.
7/2014	Hepatic glucose uptake and disposition during short-term high-fat vs. high-fructose feeding.
2/2013	Portal vein glucose entry triggers a coordinated cellular response that potentiates hepatic glucose uptake and storage in normal but not high-fat/high-fructose-fed dogs.
1/2013	Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion.
8/2009	A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin.
6/2005	Inclusion of low amounts of fructose with an intraportal glucose load increases net hepatic glucose uptake in the presence of relative insulin deficiency in dog.
7/2003	Effects of fructose on hepatic glucose metabolism.

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Alan D Cherrington Research Topics

Disease

38	Hyperglycemia 02/2024 - 02/2002
21	Hyperinsulinism (Hyperinsulinemia) 02/2023 - 02/2002
14	Hypoglycemia (Reactive Hypoglycemia) 11/2022 - 10/2002
13	Type 2 Diabetes Mellitus (MODY) 01/2023 - 07/2003
13	Insulin Resistance 01/2023 - 02/2002
8	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2023 - 10/2015
6	Glucose Intolerance 01/2023 - 12/2004
3	Metabolic Diseases (Metabolic Disease) 02/2023 - 01/2012
2	Body Weight (Weight, Body) 01/2020 - 01/2018
1	Weight Loss (Weight Reduction) 01/2023
1	Fatty Liver 01/2023
1	COVID-19 10/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021
1	Prediabetic State (Prediabetes) 01/2020
1	Mason-Type Diabetes 01/2019
1	Hyperphagia (Overeating) 05/2015
1	Weight Gain 05/2015
1	Prolapse 06/2007
1	Diarrhea 08/2005
1	Infections 07/2003

Drug/Important Bio-Agent (IBA)

51	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 02/2002
35	Insulin (Novolin)FDA Link 02/2023 - 02/2002
17	Glucagon (Glukagon)FDA Link 01/2023 - 10/2002
11	FructoseIBA 01/2023 - 02/2002
10	GlycogenIBA 01/2018 - 04/2004
7	Liver GlycogenIBA 01/2018 - 04/2004
5	Nonesterified Fatty Acids (NEFA)IBA 01/2021 - 02/2002
5	Glycogen Phosphorylase (Phosphorylase, Glycogen)IBA 01/2018 - 11/2003
4	Glycogen Synthase (Synthase I)IBA 01/2018 - 06/2010
3	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021 - 12/2016
3	GlucokinaseIBA 01/2019 - 02/2013
3	Proteins (Proteins, Gene)FDA Link 05/2015 - 06/2010
3	Serotonin (5 Hydroxytryptamine)IBA 08/2005 - 01/2004
2	salicylhydroxamic acid (SHAM)IBA 01/2021 - 06/2007
2	Glycerol (Glycerine)FDA LinkGeneric 01/2021 - 01/2020
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 11/2002
2	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2020 - 10/2003
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020 - 01/2017
2	Hormones (Hormone)IBA 01/2017 - 01/2012
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2016 - 07/2004
2	EnzymesIBA 12/2010 - 06/2010
2	Glucagon-Like Peptide 1 (GLP 1)IBA 02/2008 - 05/2003
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 03/2005 - 12/2004
2	CarbonIBA 03/2005 - 12/2004
2	Fluvoxamine (Luvox)FDA LinkGeneric 03/2005 - 12/2004
1	Amino Acids FDA Link 01/2023
1	Insulin Glargine (Lantus)FDA Link 11/2022
1	Insulin Aspart (NovoLog)FDA Link 11/2022
1	Metformin (Glucophage)FDA LinkGeneric 11/2022
1	3-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA 01/2021
1	cholesterylphosphorylethylpyridiniumIBA 01/2021
1	C-PeptideIBA 01/2021
1	fumagillinIBA 01/2020
1	methionine aminopeptidase 2IBA 01/2020
1	Hemoglobins (Hemoglobin)IBA 01/2019
1	Blood Glucose (Blood Sugar)IBA 06/2015
1	CarbohydratesIBA 05/2015
1	lixisenatideIBA 12/2013
1	Acetaminophen (Paracetamol)FDA LinkGeneric 09/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2010
1	Messenger RNA (mRNA)IBA 06/2010
1	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2010
1	Cortisone FDA Link 05/2010
1	ThiazolidinedionesIBA 01/2009
1	PPAR gammaIBA 01/2009
1	Nitric Oxide Synthase (NO Synthase)IBA 04/2008
1	5-Hydroxytryptophan (5 Hydroxytryptophan)IBA 08/2005
1	hexyl-insulin monoconjugate 2IBA 07/2005
1	Human Regular Insulin (Humulin)IBA 07/2005
1	Glucose-6-PhosphateIBA 04/2004
1	Serotonin ReceptorsIBA 01/2004
1	phospholipid emulsion soybean oil (Intralipid)IBA 02/2002
1	Acetylcholine (Acetylcholine Chloride)FDA Link 02/2002

Therapy/Procedure

5	Therapeutics 01/2023 - 01/2009
3	Glycemic Control 01/2021 - 10/2015
2	Sympathectomy (Sympathectomies) 01/2019 - 01/2006
1	Bariatric Surgery 11/2022
1	Catheters 01/2016
1	Transplantation 10/2005
1	Denervation 02/2002