Xiao Chen Selected Research

Immunotherapy

5/2024	The Single Cell Immunogenomic Landscape after Neoadjuvant Immunotherapy combined Chemotherapy in Esophageal Squamous Cell Carcinoma.
4/2024	Identification of cellular senescence-associated genes as new biomarkers for predicting the prognosis and immunotherapy response of non-small cell lung cancer and construction of a prognostic model.
2/2024	MicroRNA-124 plays an inhibitory role in cutaneous squamous cell carcinoma cells via targeting SNAI2, an immunotherapy determinant.
1/2024	SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion.
11/2023	A Dihydroartemisinin-Loaded Nanoreactor Motivates Anti-Cancer Immunotherapy by Synergy-Induced Ferroptosis to Activate Cgas/STING for Reprogramming of Macrophage.
9/2023	Model for predicting prognosis and immunotherapy based on CD+8 T cells infiltration in neuroblastoma.
9/2023	Identification of m5C-related molecular subtypes and prediction models in the prognosis and tumor microenvironment infiltration of soft tissue sarcoma.
8/2023	Elucidating the Role of Pyroptosis in Lower-Grade Glioma: Development of a Novel Scoring System to Enhance Personalized Therapeutic Approaches.
6/2023	Pyroptosis-Mediated Synergistic Photodynamic and Photothermal Immunotherapy Enabled by a Tumor-Membrane-Targeted Photosensitive Dimer.
4/2023	Cellular immunotherapy combined with platinum-based chemotherapy prolongs survival for non-small cell lung cancer patients.

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Xiao Chen Research Topics

Disease

228	Neoplasms (Cancer) 05/2024 - 06/2003
48	Inflammation (Inflammations) 04/2024 - 10/2007
44	Neoplasm Metastasis (Metastasis) 05/2024 - 07/2010
44	Infections 02/2024 - 03/2003
38	Lung Neoplasms (Lung Cancer) 05/2024 - 03/2005
32	Body Weight (Weight, Body) 04/2024 - 06/2005
27	Carcinogenesis 08/2023 - 03/2003
25	Breast Neoplasms (Breast Cancer) 04/2024 - 07/2004
24	Fibrosis (Cirrhosis) 05/2024 - 08/2013
23	Osteoporosis 03/2023 - 05/2013
22	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2024 - 07/2007
19	Hypertension (High Blood Pressure) 01/2024 - 01/2013
18	Glioma (Gliomas) 05/2024 - 06/2010
17	Hypoxia (Hypoxemia) 05/2024 - 01/2012
17	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 11/2004
16	Glioblastoma (Glioblastoma Multiforme) 05/2024 - 10/2017
16	Colorectal Neoplasms (Colorectal Cancer) 08/2022 - 06/2005
15	Heart Failure 02/2024 - 05/2015
14	Type 2 Diabetes Mellitus (MODY) 04/2024 - 01/2008
14	Carcinoma (Carcinomatosis) 01/2022 - 05/2004
13	Disease Progression 04/2024 - 01/2018
13	Cognitive Dysfunction 01/2024 - 01/2020
13	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2023 - 01/2003
12	Osteoarthritis 07/2024 - 07/2013
12	Adenocarcinoma of Lung 04/2024 - 01/2017
12	Atherosclerosis 11/2023 - 10/2013
11	Triple Negative Breast Neoplasms 04/2024 - 11/2016
11	Obesity 03/2024 - 04/2017
11	Diabetes Mellitus 01/2024 - 01/2008
11	Pain (Aches) 07/2023 - 07/2013
11	Wounds and Injuries (Trauma) 02/2022 - 01/2009
10	COVID-19 01/2023 - 01/2020
10	Infarction (Infarctions) 01/2023 - 05/2007
10	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 11/2014
9	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 07/2017
9	Tendinopathy (Tendonitis) 09/2023 - 04/2016
9	Neuroinflammatory Diseases 08/2023 - 01/2020
9	Myocarditis (Carditis) 08/2023 - 02/2017
9	Non-alcoholic Fatty Liver Disease 07/2023 - 11/2015
9	Stroke (Strokes) 09/2021 - 05/2007
8	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2024 - 04/2011
8	Melanoma (Melanoma, Malignant) 01/2024 - 01/2018
8	Colonic Neoplasms (Colon Cancer) 10/2023 - 02/2007
8	Lymphatic Metastasis 01/2023 - 07/2004
7	Bites and Stings (Sting) 05/2024 - 01/2022
7	Critical Illness (Critically Ill) 05/2024 - 11/2012

Drug/Important Bio-Agent (IBA)

63	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2013
60	Biomarkers (Surrogate Marker)IBA 05/2024 - 07/2012
29	Therapeutic UsesIBA 04/2024 - 05/2010
23	RNA (Ribonucleic Acid)IBA 05/2024 - 09/2009
23	VaccinesIBA 01/2023 - 06/2003
22	MicroRNAs (MicroRNA)IBA 05/2024 - 09/2009
19	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 01/2008
18	CollagenIBA 10/2023 - 07/2012
16	Tacrolimus (Prograf)FDA LinkGeneric 04/2024 - 01/2014
15	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2024 - 01/2015
15	AntigensIBA 06/2023 - 01/2008
15	Messenger RNA (mRNA)IBA 02/2023 - 01/2012
15	CadmiumIBA 06/2022 - 11/2011
14	CytokinesIBA 05/2024 - 11/2004
14	LipidsIBA 03/2024 - 10/2017
13	Peptides (Polypeptides)IBA 08/2023 - 01/2012
12	Indicators and Reagents (Reagents)IBA 04/2024 - 11/2004
12	AntioxidantsIBA 12/2023 - 03/2011
12	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 01/2012
11	Interleukin-6 (Interleukin 6)IBA 05/2024 - 07/2009
11	Sirolimus (Rapamycin)FDA Link 03/2024 - 07/2019
10	Hemoglobins (Hemoglobin)IBA 04/2024 - 01/2008
10	Immune Checkpoint InhibitorsIBA 01/2024 - 03/2020
10	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2023 - 12/2013
10	Long Noncoding RNAIBA 12/2022 - 07/2019
9	Phenobarbital (Luminal)FDA Link 05/2024 - 04/2011
9	CholesterolIBA 01/2024 - 10/2017
9	Phosphotransferases (Kinase)IBA 12/2023 - 03/2005
9	1-phenyl-3,3-dimethyltriazene (PDT)IBA 02/2023 - 01/2021
9	EnzymesIBA 01/2023 - 07/2007
9	Interleukin-10 (Interleukin 10)IBA 01/2023 - 11/2004
9	CurcuminIBA 02/2022 - 08/2015
9	Capsules (Microcapsules)IBA 08/2020 - 02/2017
8	AntibodiesIBA 05/2024 - 12/2008
8	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2024 - 04/2019
8	ChromatinIBA 01/2024 - 01/2021
8	C-Reactive ProteinIBA 01/2024 - 05/2016
8	InterferonsIBA 12/2023 - 04/2011
8	polyglycerolIBA 12/2023 - 07/2014
8	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 01/2014
8	Oxygen (Dioxygen)IBA 10/2023 - 10/2011
8	Transcription Factors (Transcription Factor)IBA 09/2023 - 03/2015
8	NF-kappa B (NF-kB)IBA 08/2023 - 10/2019
7	artenimol (dihydroartemisinin)IBA 05/2024 - 10/2020

Therapy/Procedure

123	Therapeutics 05/2024 - 05/2004
37	Drug Therapy (Chemotherapy) 05/2024 - 09/2011
31	Immunotherapy 05/2024 - 05/2015
13	Radiotherapy 01/2024 - 01/2016
13	Transplantation 01/2024 - 01/2003
13	Chinese Traditional Medicine (Traditional Chinese Medicine) 09/2023 - 01/2013
12	Photochemotherapy (Photodynamic Therapy) 12/2023 - 01/2021
10	Hematopoietic Stem Cell Transplantation 01/2023 - 12/2016
9	Lasers (Laser) 03/2024 - 06/2004
9	Length of Stay 09/2023 - 11/2014