Joseph Chao Selected Research

Drug Therapy (Chemotherapy)

5/2024	First-Line Nivolumab and Relatlimab Plus Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma: The Phase II RELATIVITY-060 Study.
11/2023	Safety and Efficacy of Oxaliplatin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Colorectal and Appendiceal Cancer with Peritoneal Metastases: Results of a Multicenter Phase I Trial in the USA.
11/2023	ASO Visual Abstract: Safety and Efficacy of Oxaliplatin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Colorectal and Appendiceal Cancer with Peritoneal Metastases: Results of a Multicenter Phase I Trial in the United States.
1/2023	Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gastrointestinal cancer.
1/2023	Outcomes and a prognostic classifier in patients with microsatellite instability-high metastatic gastric cancer receiving PD-1 blockade.
1/2023	Trastuzumab deruxtecan in patients in the USA and Europe with HER2-positive advanced gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (DESTINY-Gastric02): primary and updated analyses from a single-arm, phase 2 study.
11/2022	Current landscape of radiation oncology in esophageal cancer: a narrative review.
2/2022	Chemotherapy predictors and a time-dependent chemotherapy effect in metastatic esophageal cancer.
1/2022	Immunotherapy-Based Neoadjuvant Treatment of Advanced Microsatellite Instability-High Gastric Cancer: A Case Series.
1/2022	Association of Tumor Mutational Burden with Efficacy of Pembrolizumab±Chemotherapy as First-Line Therapy for Gastric Cancer in the Phase III KEYNOTE-062 Study.

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Joseph Chao Research Topics

Disease

59	Neoplasms (Cancer) 05/2024 - 02/2010
25	Stomach Neoplasms (Stomach Cancer) 05/2024 - 06/2015
16	Adenocarcinoma 05/2024 - 02/2015
8	Microsatellite Instability 01/2023 - 07/2018
6	Neoplasm Metastasis (Metastasis) 11/2023 - 01/2020
6	Esophageal Neoplasms (Esophageal Cancer) 11/2022 - 10/2008
5	Disease Progression 12/2023 - 01/2022
5	Breast Neoplasms (Breast Cancer) 10/2017 - 09/2014
4	Colorectal Neoplasms (Colorectal Cancer) 12/2023 - 10/2017
3	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2023 - 09/2014
2	Appendiceal Neoplasms (Appendix Cancer) 11/2023 - 11/2023
2	Colitis 01/2022 - 01/2022
2	Carcinoma (Carcinomatosis) 10/2019 - 01/2017
2	Weight Loss (Weight Reduction) 01/2019 - 09/2004
1	Hematologic Neoplasms (Hematological Malignancy) 02/2024
1	Leukemia 02/2024
1	Lymphoma (Lymphomas) 02/2024
1	Hypoxia (Hypoxemia) 12/2023
1	Ascites 01/2022
1	Circulating Neoplastic Cells 01/2019
1	Liver Diseases (Liver Disease) 01/2019
1	Chest Pain (Chest Pains) 12/2017

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2017
11	Immune Checkpoint InhibitorsIBA 01/2023 - 07/2018
9	pembrolizumabIBA 01/2022 - 07/2018
6	PlatinumIBA 01/2022 - 01/2016
5	Trastuzumab (Herceptin)FDA Link 01/2023 - 02/2015
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2023 - 01/2022
4	B7-H1 AntigenIBA 01/2022 - 07/2018
4	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 10/2017
4	IT-101IBA 12/2017 - 08/2013
3	Circulating Tumor DNAIBA 02/2024 - 01/2018
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 09/2014
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017 - 09/2014
2	RamucirumabIBA 12/2023 - 02/2015
2	human ERBB2 proteinIBA 06/2023 - 01/2023
2	Fluorouracil (Carac)FDA LinkGeneric 01/2023 - 01/2022
2	Monoclonal AntibodiesIBA 01/2023 - 01/2019
2	Leucovorin (Folinic Acid)FDA Link 01/2023 - 01/2022
2	Cell-Free Nucleic AcidsIBA 01/2020 - 01/2019
2	Interleukin-6 (Interleukin 6)IBA 10/2017 - 08/2017
2	Blood Coagulation Factors (Coagulation Factor)IBA 10/2017 - 08/2017
2	fibrin fragment D (D-dimer)IBA 10/2017 - 08/2017
2	CamptothecinIBA 04/2016 - 08/2013
2	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 04/2016 - 09/2013
2	Imatinib Mesylate (Gleevec)FDA Link 08/2010 - 02/2010
1	relatlimabIBA 05/2024
1	NivolumabIBA 05/2024
1	Chimeric Antigen ReceptorsIBA 02/2024
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2023
1	olaparibIBA 12/2023
1	trifluridine tipiracil drug combinationIBA 12/2023
1	regorafenibIBA 12/2023
1	sotorasibIBA 12/2023
1	Panitumumab (Vectibix)FDA Link 12/2023
1	Immunoconjugates (Immunoconjugate)IBA 01/2023
1	zolbetuximabIBA 01/2023
1	trastuzumab deruxtecanIBA 01/2023
1	Protein Isoforms (Isoforms)IBA 01/2023
1	NucleotidesIBA 06/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 07/2021
1	Immunomodulating AgentsIBA 07/2021
1	LigandsIBA 10/2020
1	durvalumabIBA 01/2020
1	Yttrium-90IBA 01/2020
1	tremelimumabIBA 01/2020
1	tyrosine receptor (receptor, tyrosine)IBA 11/2019
1	Phosphotransferases (Kinase)IBA 11/2019
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2019
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 10/2019
1	Vinorelbine (Navelbine)FDA LinkGeneric 01/2019
1	4-O-deacetyl vinorelbineIBA 01/2019
1	130-nm albumin-bound paclitaxelIBA 01/2019
1	BilirubinIBA 01/2019
1	SaltsIBA 12/2018
1	XELOXIBA 12/2018
1	Irinotecan (Camptosar)FDA LinkGeneric 12/2017
1	binimetinibIBA 10/2017
1	C-Reactive ProteinIBA 10/2017

Therapy/Procedure

33	Therapeutics 01/2023 - 02/2010
32	Drug Therapy (Chemotherapy) 05/2024 - 08/2010
14	Immunotherapy 01/2023 - 06/2018
7	Neoadjuvant Therapy 11/2022 - 10/2008
5	Adjuvant Chemotherapy 01/2019 - 06/2015
4	Radiotherapy 01/2022 - 06/2015
3	Cytoreduction Surgical Procedures 11/2023 - 01/2017
2	Hyperthermic Intraperitoneal Chemotherapy 01/2022 - 01/2017
2	Precision Medicine 01/2020 - 01/2020
2	Lymph Node Excision (Lymph Node Dissection) 01/2019 - 06/2015
1	Gastrectomy 01/2023
1	Proton Therapy 11/2022
1	Palliative Care (Palliative Therapy) 09/2020
1	Aftercare (After-Treatment) 01/2020
1	Microspheres (Microsphere) 01/2020
1	Esophagectomy 08/2019
1	Pancreatectomy 01/2019
1	Splenectomy 01/2019
1	Activities of Daily Living (ADL) 10/2017