Qing Chang Selected Research

Breast Neoplasms (Breast Cancer)

5/2024	eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
2/2023	Novel diagnostic biomarkers of T cell-mediated tumor killing characteristics for early-stage triple negative breast cancer: A SEER analysis and molecular portraits.
8/2022	ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance.
1/2022	INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors.
10/2017	Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.
1/2017	Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.
2/2016	Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.
7/2013	The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.
1/2011	Stat3 mediates expression of autotaxin in breast cancer.
11/2002	Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: therapeutic implications.

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Qing Chang Research Topics

Disease

96	Neoplasms (Cancer) 05/2024 - 11/2002
28	Infections 03/2024 - 07/2003
25	Inflammation (Inflammations) 02/2024 - 05/2003
14	Pancreatic Neoplasms (Pancreatic Cancer) 11/2022 - 01/2004
13	Neoplasm Metastasis (Metastasis) 01/2023 - 04/2006
11	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 07/2007
11	Fibrosis (Cirrhosis) 01/2022 - 01/2016
10	Breast Neoplasms (Breast Cancer) 05/2024 - 11/2002
10	Deafness (Deaf Mutism) 01/2016 - 12/2006
9	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 02/2008
9	Lung Neoplasms (Lung Cancer) 01/2023 - 04/2009
8	Carcinogenesis 04/2024 - 01/2011
8	Hypertension (High Blood Pressure) 03/2024 - 06/2003
8	Prostatic Neoplasms (Prostate Cancer) 10/2021 - 05/2012
7	Medulloblastoma 01/2024 - 03/2004
7	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 06/2010
6	Chronic Obstructive Pulmonary Disease (COPD) 04/2024 - 03/2020
6	Non-alcoholic Fatty Liver Disease 06/2023 - 11/2015
6	Stroke (Strokes) 01/2023 - 06/2003
6	Lymphoma (Lymphomas) 01/2023 - 01/2016
6	Retinal Detachment (Retinal Detachments) 01/2022 - 12/2012
6	Hemorrhage 01/2022 - 07/2003
5	COVID-19 03/2024 - 01/2021
5	Hypoxia (Hypoxemia) 03/2023 - 01/2004
5	Spotted Fever Group Rickettsiosis (Rickettsialpox) 01/2023 - 06/2013
5	Adenocarcinoma 11/2022 - 01/2012
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2022 - 01/2021
5	Wounds and Injuries (Trauma) 01/2022 - 07/2003
5	Atherosclerosis 01/2021 - 07/2014
5	Diabetic Retinopathy (Retinopathy, Diabetic) 02/2020 - 10/2010
4	Hyperglycemia 10/2023 - 01/2012
4	Bacterial Infections (Bacterial Infection) 09/2023 - 11/2019
4	Adenocarcinoma of Lung 05/2023 - 03/2016
4	Triple Negative Breast Neoplasms 02/2023 - 01/2019
4	Atrial Fibrillation 01/2023 - 01/2022
4	Cardiovascular Diseases (Cardiovascular Disease) 12/2022 - 06/2003
4	Central Serous Chorioretinopathy 10/2022 - 03/2019
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2019
4	Macular Degeneration (Age-Related Maculopathy) 12/2021 - 03/2014
4	Ischemia 01/2021 - 08/2014
4	Hearing Loss (Hearing Impairment) 01/2021 - 02/2009
4	Endophthalmitis (Ophthalmia) 11/2020 - 07/2013
4	Asthma (Bronchial Asthma) 09/2020 - 03/2014
4	Myocardial Infarction 10/2019 - 08/2009
4	Carcinoma (Carcinomatosis) 01/2019 - 01/2005
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2011 - 02/2009
3	Disease Progression 03/2024 - 01/2021
3	Liver Neoplasms (Liver Cancer) 12/2023 - 06/2010
3	Glioma (Gliomas) 10/2023 - 05/2013
3	Insulin Resistance 10/2023 - 10/2016
3	Gestational Diabetes (Gestational Diabetes Mellitus) 10/2023 - 01/2022

Drug/Important Bio-Agent (IBA)

36	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2007
23	Biomarkers (Surrogate Marker)IBA 01/2024 - 07/2007
18	Retinaldehyde (Retinal)IBA 01/2024 - 01/2012
16	MicroRNAs (MicroRNA)IBA 01/2023 - 01/2012
11	Interleukin-6 (Interleukin 6)IBA 03/2024 - 07/2013
11	Messenger RNA (mRNA)IBA 01/2022 - 05/2003
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 02/2004
10	CytokinesIBA 01/2023 - 02/2010
8	RNA (Ribonucleic Acid)IBA 08/2023 - 01/2016
8	DNA (Deoxyribonucleic Acid)IBA 08/2022 - 03/2008
8	Tyrosine Kinase InhibitorsIBA 01/2021 - 03/2016
7	Long Noncoding RNAIBA 01/2023 - 01/2019
7	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2016
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 05/2003
6	ChemokinesIBA 08/2023 - 01/2016
6	CollagenIBA 12/2019 - 01/2008
5	Uric Acid (Urate)IBA 04/2024 - 04/2022
5	EnzymesIBA 08/2023 - 05/2003
5	Therapeutic UsesIBA 01/2023 - 01/2004
5	Monoclonal AntibodiesIBA 10/2020 - 06/2010
5	PlatinumIBA 01/2020 - 03/2015
4	LigandsIBA 05/2024 - 09/2013
4	CarbohydratesIBA 05/2023 - 12/2019
4	cadherin 5IBA 04/2023 - 01/2023
4	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2018
4	Ranibizumab (Lucentis)FDA Link 12/2022 - 01/2019
4	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2022 - 03/2014
4	oxidized low density lipoproteinIBA 10/2022 - 11/2015
4	C-Reactive ProteinIBA 10/2022 - 10/2020
4	Caspase 3 (Caspase-3)IBA 10/2020 - 08/2003
4	Peptides (Polypeptides)IBA 01/2020 - 07/2008
4	Cisplatin (Platino)FDA LinkGeneric 12/2019 - 03/2015
4	ConnexinsIBA 01/2015 - 02/2009
4	VaccinesIBA 10/2014 - 12/2009
3	Hormones (Hormone)IBA 05/2024 - 01/2017
3	Estrogen Receptor alphaIBA 05/2024 - 01/2017
3	Cell-Free Nucleic AcidsIBA 02/2024 - 01/2022
3	Bevacizumab (Avastin)FDA Link 10/2023 - 01/2019
3	Anti-Bacterial Agents (Antibiotics)IBA 09/2023 - 01/2020

Therapy/Procedure

44	Therapeutics 12/2023 - 09/2009
15	Drug Therapy (Chemotherapy) 01/2023 - 01/2003
12	Vitrectomy 01/2022 - 07/2013
11	Injections 01/2023 - 01/2004
8	Immunotherapy 01/2022 - 10/2013
8	Transplantation 01/2020 - 04/2006
6	Aftercare (After-Treatment) 01/2022 - 01/2014
5	Photochemotherapy (Photodynamic Therapy) 10/2022 - 03/2019
4	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2023 - 01/2022
4	Radiotherapy 01/2022 - 01/2016