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Leandro Cerchietti Selected Research

Anaplastic Lymphoma Kinase

11/2016Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.
4/2011Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas.

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Leandro Cerchietti Research Topics

Disease

33Neoplasms (Cancer)
03/2024 - 02/2007
22Lymphoma (Lymphomas)
01/2024 - 12/2004
12B-Cell Lymphoma (Lymphoma, B Cell)
01/2022 - 12/2004
7Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2022 - 06/2010
5Leukemia
10/2020 - 10/2011
3T-Cell Lymphoma (Lymphoma, T Cell)
01/2022 - 01/2015
3Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
06/2020 - 11/2016
2Multiple Myeloma
01/2023 - 01/2018
2Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
06/2020 - 11/2016
2Oncogene Addiction
10/2019 - 01/2016
2Lung Neoplasms (Lung Cancer)
01/2017 - 04/2008
2Breast Neoplasms (Breast Cancer)
12/2014 - 05/2009
2Triple Negative Breast Neoplasms
07/2014 - 05/2009
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2011 - 09/2011
1Inflammation (Inflammations)
01/2023
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
01/2022
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2022
1Hypothyroidism
01/2022
1Frailty
01/2022
1Brain Neoplasms (Brain Tumor)
11/2021
1Neoplasm Metastasis (Metastasis)
01/2020
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
11/2018
1Genetic Translocation (Chromosomal Translocation)
01/2016
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
12/2015
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2015

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
11/2015 - 09/2011
5Peptides (Polypeptides)IBA
12/2015 - 12/2004
4IntegrinsIBA
01/2022 - 01/2015
4LigandsIBA
07/2017 - 08/2014
46- amino- 8- ((6- iodo- 1,3- benzodioxol- 5- yl)thio)- N- (1- methylethyl)- 9H-purine-9-propanamineIBA
11/2015 - 05/2009
3Azacitidine (5 Azacytidine)FDA Link
01/2022 - 01/2016
3Lysine (L-Lysine)FDA Link
10/2019 - 01/2018
3Histone Deacetylase InhibitorsIBA
02/2018 - 07/2014
2Messenger RNA (mRNA)IBA
10/2023 - 04/2019
2cc-486IBA
01/2023 - 01/2022
2Sirtuin 3IBA
01/2022 - 10/2019
2Antineoplastic Agents (Antineoplastics)IBA
01/2022 - 02/2018
2Adenosine Triphosphate (ATP)IBA
11/2021 - 11/2015
2DNA (Deoxyribonucleic Acid)IBA
01/2021 - 09/2013
2Eukaryotic Initiation Factor-4EIBA
10/2020 - 02/2016
2EnzymesIBA
04/2019 - 07/2014
2PanobinostatIBA
02/2018 - 12/2015
2HydrogelsIBA
07/2017 - 12/2015
2Biocompatible Materials (Biomaterials)IBA
07/2017 - 12/2015
2Anaplastic Lymphoma KinaseIBA
11/2016 - 04/2011
2ProteomeIBA
08/2014 - 09/2011
2Transcription Factors (Transcription Factor)IBA
07/2014 - 02/2007
2Glucose (Dextrose)FDA LinkGeneric
02/2014 - 07/2013
2Oxygen (Dioxygen)IBA
02/2014 - 07/2013
2Tyrosine Kinase InhibitorsIBA
06/2013 - 10/2011
2Oncogene Proteins (Oncogene Protein)IBA
09/2011 - 05/2009
1ChromatinIBA
03/2024
1RibonucleoproteinsIBA
01/2024
1Histamine H4 ReceptorsIBA
01/2022
1Histamine (Histamine Dihydrochloride)FDA Link
01/2022
1Bexarotene (LGD1069)FDA Link
01/2022
1AnthracyclinesIBA
01/2022
1Thyroxine (Levothyroxine)FDA LinkGeneric
01/2022
1Amino AcidsFDA Link
01/2022
1Untranslated RNA (Noncoding RNA)IBA
01/2022
1Retinoid X Receptors (Retinoid X Receptor)IBA
01/2022
1Arginine (L-Arginine)FDA Link
11/2021
1Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2021
1Nitric Oxide Synthase (NO Synthase)IBA
11/2021
1Lactic Acid (Lactate)FDA LinkGeneric
11/2021
1Multiprotein ComplexesIBA
10/2021
1Janus Kinase InhibitorsIBA
06/2020
1ruxolitinibIBA
06/2020
1Doxorubicin (Adriamycin)FDA LinkGeneric
04/2019
1Thyroid HormonesIBA
04/2019
1Cytotoxins (Cytolysins)IBA
01/2019
1Lenalidomide (CC 5013)FDA Link
11/2018
1Rituximab (Mabthera)FDA Link
11/2018
1Choline (Choline Chloride)IBA
02/2018
1Histones (Histone)IBA
01/2018
1Cell Surface ReceptorsIBA
07/2017
1Small Interfering RNA (siRNA)IBA
06/2017
1Drug CombinationsIBA
01/2017
1obatoclaxIBA
01/2017
1OTX015IBA
11/2016
1RNA (Ribonucleic Acid)IBA
02/2016
1DecitabineFDA Link
01/2016
1VorinostatFDA Link
01/2016
1Indicators and Reagents (Reagents)IBA
12/2015
1Syk KinaseIBA
12/2015
1Protein Isoforms (Isoforms)IBA
11/2015
1ibrutinibIBA
11/2015
1AICA ribonucleotide (ZMP)IBA
11/2015
1Excipients (Suspending Agents)IBA
11/2015
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
11/2015
1Progesterone Receptors (Progesterone Receptor)IBA
12/2014
1Progestins (Progestagens)IBA
12/2014
1Cyclin A2IBA
12/2014
1Biomarkers (Surrogate Marker)IBA
12/2014

Therapy/Procedure

19Therapeutics
01/2022 - 02/2007
7Drug Therapy (Chemotherapy)
04/2019 - 04/2008
5Immunotherapy
03/2024 - 09/2015
2Radiotherapy
11/2021 - 04/2008
1Breast Implants (Breast Implant)
06/2020
1Precision Medicine
06/2020