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Robert D Burgoyne Selected Research

Resveratrol

11/2014Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.

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Robert D Burgoyne Research Topics

Disease

6Neurodegenerative Diseases (Neurodegenerative Disease)
10/2018 - 02/2012
2Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
09/2015 - 11/2014
1Epilepsy (Aura)
11/2018
1TDP-43 Proteinopathies
10/2018
1Dystonia (Limb Dystonia)
01/2017
1Seizures (Absence Seizure)
09/2015
1Dementia (Dementias)
09/2015
1Movement Disorders (Movement Disorder)
09/2015
1Alzheimer Disease (Alzheimer's Disease)
02/2012
1Ataxia (Dyssynergia)
02/2012
1Huntington Disease (Huntington's Disease)
02/2012
1Parkinson Disease (Parkinson's Disease)
02/2012
1Hypersensitivity (Allergy)
03/2011
1Autism Spectrum Disorder
05/2010
1Alcoholism (Alcohol Abuse)
02/2010
1Vesicular Stomatitis
11/2005
1Cognitive Dysfunction
06/2003
1X-Linked Mental Retardation (Mental Retardation, X Linked)
06/2003

Drug/Important Bio-Agent (IBA)

3CalciumIBA
01/2017 - 06/2003
3Proteins (Proteins, Gene)FDA Link
09/2015 - 06/2003
2Ethosuximide (Zarontin)FDA LinkGeneric
10/2015 - 09/2015
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
09/2015 - 02/2012
2UbiquitinIBA
09/2015 - 02/2012
1Anticonvulsants (Antiepileptic Drugs)IBA
11/2018
1methsuximide (mesuximide)FDA Link
10/2018
1HippocalcinIBA
01/2017
1CeroidIBA
09/2015
1ResveratrolIBA
11/2014
1Neuroprotective AgentsIBA
11/2014
1SirtuinsIBA
11/2014
1polyglutamineIBA
02/2012
1peroxisomal acyl-CoA oxidaseIBA
02/2012
1EnzymesIBA
02/2012
1Histone Deacetylases (Histone Deacetylase)IBA
02/2012
1Aldicarb (Temik)IBA
03/2011
1Ethanol (Ethyl Alcohol)IBA
02/2010
1Glycoproteins (Glycoprotein)IBA
11/2005
1Guanosine Triphosphate (GTP)IBA
11/2005
1Coat Protein Complex I (COPI)IBA
11/2005
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
06/2003

Therapy/Procedure

2Therapeutics
04/2015 - 02/2012