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Herbert Budka Selected Research

Protein Isoforms (Isoforms)

1/2012Prion protein (PrP) deposits in the tectum of experimental Gerstmann-Sträussler-Scheinker disease following intraocular inoculation.
6/2006Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.
12/2002Disease-associated prion protein in vessel walls.
9/2002Distribution of intraneuronal immunoreactivity for the prion protein in human prion diseases.

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Herbert Budka Research Topics

Disease

36Prion Diseases (Transmissible Spongiform Encephalopathies)
10/2020 - 01/2002
22Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
01/2020 - 01/2002
16Neurodegenerative Diseases (Neurodegenerative Disease)
10/2020 - 09/2002
14Alzheimer Disease (Alzheimer's Disease)
01/2017 - 01/2002
12Multiple System Atrophy
09/2014 - 09/2002
12Neoplasms (Cancer)
10/2007 - 03/2002
11Parkinson Disease (Parkinson's Disease)
09/2014 - 03/2002
8Sporadic Creutzfeldt-Jakob Disease
01/2015 - 01/2004
8Dementia (Dementias)
09/2014 - 04/2006
7Infections
01/2017 - 02/2004
7Acquired CJD
12/2013 - 05/2003
6Lewy Body Disease (Lewy Body Dementia)
07/2012 - 03/2002
6Synucleinopathies
07/2012 - 11/2004
6Glioblastoma (Glioblastoma Multiforme)
04/2007 - 07/2002
5Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
10/2020 - 09/2002
5Multiple Sclerosis
03/2016 - 02/2004
4Scrapie
01/2017 - 09/2005
4Inclusion Body Myositis
01/2013 - 01/2004
4Ependymoma
04/2007 - 07/2004
3Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
01/2021 - 09/2009
3Encephalitis (Encephalitis, Rasmussen)
01/2018 - 02/2009
3Atrophy
08/2017 - 03/2003
3Gliosis
09/2014 - 03/2006
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2012 - 12/2004
3Disease Progression
09/2011 - 04/2004
3Amyloid Plaque
09/2011 - 04/2002
3Astrocytoma (Pilocytic Astrocytoma)
04/2007 - 11/2003
2Tauopathies
10/2016 - 08/2011
2Progressive Multifocal Leukoencephalopathy
10/2013 - 02/2004
2Dermatomyositis (Dermatopolymyositis)
01/2013 - 07/2008
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
03/2012 - 09/2007
2Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
01/2012 - 03/2006
2Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
10/2010 - 11/2007
2Motor Neuron Disease (Primary Lateral Sclerosis)
09/2010 - 09/2002
2Demyelinating Diseases (Demyelinating Disease)
06/2008 - 09/2003
2Inflammation (Inflammations)
06/2008 - 09/2007
2Guillain-Barre Syndrome
06/2008 - 10/2006
2Neuroblastoma
04/2007 - 07/2003
2Medulloblastoma
04/2007 - 11/2006
2Lymphoma (Lymphomas)
04/2007 - 10/2006
2Oligodendroglioma
04/2007 - 03/2002
2Brain Ischemia (Cerebral Ischemia)
03/2006 - 12/2002
2Hypoxia (Hypoxemia)
02/2005 - 04/2003
2Necrosis
01/2005 - 07/2004
2Fatal Familial Insomnia
11/2002 - 01/2002
1COVID-19
01/2023
1Glioma (Gliomas)
01/2018
1Parasomnias (Parasomnia)
10/2016
1Respiratory Sounds (Crackle)
10/2016
1Sleep Apnea Syndromes (Sleep Apnea)
10/2016
1Hypertension (High Blood Pressure)
09/2016
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2016
1Cognitive Dysfunction
01/2016
1Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
01/2016
1Proteostasis Deficiencies
01/2016
1Central Nervous System Diseases (CNS Diseases)
10/2013

Drug/Important Bio-Agent (IBA)

33Prion ProteinsIBA
10/2020 - 01/2002
27Proteins (Proteins, Gene)FDA Link
01/2017 - 07/2002
13PrionsIBA
10/2020 - 01/2004
9Amyloid (Amyloid Fibrils)IBA
01/2016 - 06/2003
814-3-3 Proteins (14-3-3 Protein)IBA
12/2013 - 03/2002
6alpha-SynucleinIBA
10/2008 - 11/2004
6ParaffinIBA
11/2006 - 12/2002
5AntibodiesIBA
10/2016 - 09/2003
5Codon (Codons)IBA
11/2011 - 11/2002
4SynucleinsIBA
09/2014 - 01/2008
4Protein Isoforms (Isoforms)IBA
01/2012 - 09/2002
3CytokinesIBA
01/2023 - 08/2009
3Biomarkers (Surrogate Marker)IBA
01/2017 - 04/2010
3Cathepsin DIBA
03/2013 - 07/2007
3TubulinIBA
11/2010 - 11/2004
3Peptide Hydrolases (Proteases)FDA Link
06/2006 - 09/2005
3Formaldehyde (Formol)FDA Link
03/2006 - 12/2002
2Protein AggregatesIBA
01/2021 - 01/2012
2tau Proteins (tau Protein)IBA
10/2020 - 08/2011
2Messenger RNA (mRNA)IBA
01/2017 - 02/2005
2Natalizumab (Tysabri)FDA Link
03/2016 - 10/2013
2Growth Hormone (Somatotropin)IBA
01/2016 - 05/2012
2Endopeptidase K (Proteinase K)IBA
11/2013 - 03/2009
2Monoclonal AntibodiesIBA
10/2013 - 01/2002
2Heat-Shock Proteins (Heat-Shock Protein)IBA
06/2008 - 03/2006
2AntigensIBA
06/2008 - 07/2004
2SurvivinIBA
10/2005 - 05/2005
2Amyloid beta-PeptidesIBA
09/2005 - 04/2002
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2005 - 04/2003
2Mitochondrial DNA (mtDNA)IBA
01/2005 - 03/2003
2trioctyl phosphine oxide (TOPO)IBA
07/2004 - 03/2002
2Complement System Proteins (Complement)IBA
02/2004 - 09/2003
2Type I DNA Topoisomerases (Topoisomerase I)IBA
07/2002 - 03/2002
1SphingolipidsIBA
10/2020
1Histones (Histone)IBA
01/2018
1lipopigmentsIBA
08/2017
1CystatinsIBA
01/2017
1Apolipoprotein E4IBA
01/2016
1NADPH Oxidases (NAD(P)H oxidase)IBA
12/2014
1Glutamate Receptors (Glutamate Receptor)IBA
01/2014

Therapy/Procedure

3Therapeutics
09/2016 - 04/2002
2Drug Therapy (Chemotherapy)
07/2002 - 03/2002
1Transplantation
01/2020
1Aftercare (After-Treatment)
01/2016