Hermine I Brunner Selected Research

Cytokines

1/2023	Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy.
1/2021	Immunomodulatory effects of cytokine-induced expansion of cytotoxic lymphocytes in a mouse model of lupus-like disease.
6/2020	Prevalence of co-existing autoimmune disease in juvenile idiopathic arthritis: a cross-sectional study.
3/2004	An ACE inhibitor reduces Th2 cytokines and TGF-beta1 and TGF-beta2 isoforms in murine lupus nephritis.
2/2002	Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue.

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Hermine I Brunner Research Topics

Disease

53	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 03/2024 - 02/2002
31	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2023 - 06/2003
18	Lupus Nephritis 01/2023 - 03/2004
11	Infections 11/2021 - 12/2009
7	Arthritis (Polyarthritis) 12/2023 - 12/2012
7	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 01/2011
6	Body Weight (Weight, Body) 01/2021 - 12/2012
5	Macrophage Activation Syndrome 11/2019 - 03/2007
4	Fever (Fevers) 12/2020 - 12/2012
3	Rheumatoid Arthritis 10/2023 - 06/2015
3	Uveitis 12/2022 - 12/2015
3	Proteinuria 01/2021 - 03/2004
3	Neoplasms (Cancer) 01/2021 - 07/2005
3	Rheumatic Diseases (Rheumatism) 12/2020 - 12/2015
3	Nephritis 12/2007 - 03/2004
2	Acute Kidney Injury (Acute Renal Failure) 01/2023 - 08/2006
2	Psoriatic Arthritis 01/2023 - 12/2020
2	Kidney Diseases (Kidney Disease) 01/2023 - 02/2002
2	Neutropenia 01/2019 - 12/2012
2	Hypertension (High Blood Pressure) 03/2004 - 02/2002
1	Vasculitis (Vasculitides) 05/2024
1	Breakthrough Infections 12/2023
1	Pulmonary Embolism 12/2023
1	Axial Spondyloarthritis 01/2023
1	Anterior Uveitis 12/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2022
1	Inflammation (Inflammations) 01/2022
1	Negative rheumatoid factor polyarthritis 11/2021
1	Pain (Aches) 01/2021
1	Multiple Sclerosis 01/2021
1	Glomerulonephritis 06/2020
1	Sjogren's Syndrome (Sjogren Syndrome) 06/2020
1	Diphtheria 02/2020
1	Tetanus 02/2020
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2020
1	Macular Degeneration (Age-Related Maculopathy) 01/2019
1	Myocardial Infarction 01/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019

Drug/Important Bio-Agent (IBA)

17	Biomarkers (Surrogate Marker)IBA 01/2023 - 08/2006
11	Methotrexate (Mexate)FDA LinkGeneric 11/2023 - 12/2009
10	tocilizumab (atlizumab)FDA Link 03/2024 - 12/2012
10	Proteins (Proteins, Gene)FDA Link 01/2023 - 07/2005
8	Abatacept (Orencia)FDA Link 01/2024 - 01/2018
7	C-Reactive ProteinIBA 11/2023 - 12/2012
6	Antirheumatic Agents (DMARD)IBA 12/2023 - 01/2020
5	Rheumatoid FactorIBA 12/2023 - 06/2012
5	CytokinesIBA 01/2023 - 02/2002
5	Lipocalin-2IBA 01/2023 - 08/2006
5	GlucocorticoidsIBA 01/2021 - 12/2012
5	canakinumab FDA Link 12/2020 - 12/2012
5	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2020 - 01/2011
5	CreatinineIBA 01/2019 - 08/2006
4	S100A12 ProteinIBA 01/2022 - 10/2017
3	AdiponectinIBA 01/2023 - 01/2019
3	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2023 - 01/2012
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 02/2002
3	tofacitinibIBA 01/2022 - 12/2017
3	chlorotriphenylsilane (CTPS)IBA 01/2019 - 03/2012
2	Ceruloplasmin (Ferroxidase)IBA 01/2023 - 01/2022
2	HemopexinIBA 01/2023 - 01/2022
2	secukinumabIBA 01/2023 - 01/2022
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2023 - 01/2022
2	SteroidsIBA 01/2022 - 08/2013
2	golimumab FDA Link 10/2021 - 01/2018
2	belimumabIBA 01/2021 - 10/2020
2	Adalimumab (Humira)FDA Link 10/2020 - 01/2020
2	VaccinesIBA 02/2020 - 01/2020
2	S100 Proteins (S 100 Protein)IBA 01/2020 - 10/2017
2	Immunosuppressive Agents (Immunosuppressants)IBA 10/2019 - 01/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 01/2018
2	Antinuclear AntibodiesIBA 12/2015 - 05/2012
2	AutoantibodiesIBA 12/2015 - 01/2015
2	Prednisone (Sone)FDA LinkGeneric 10/2011 - 05/2009
2	EnzymesIBA 03/2008 - 03/2007
2	ImmunosorbentsIBA 03/2008 - 03/2007
1	baricitinibIBA 12/2023
1	Janus Kinase 1IBA 12/2023
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2023
1	AutoantigensIBA 01/2023
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2023
1	InterferonsIBA 01/2023
1	RNA (Ribonucleic Acid)IBA 01/2023
1	ixekizumabIBA 01/2022
1	Certolizumab Pegol FDA Link 01/2022
1	Estrogens (Estrogen)FDA Link 01/2021
1	ametantrone (HAQ)IBA 01/2021
1	Daclizumab (Zenapax)FDA Link 01/2021
1	ORALIT (ORS)IBA 06/2020
1	Diphtheria-Tetanus VaccineIBA 02/2020
1	Interleukin-18 (Interleukin 18)IBA 11/2019
1	Antimalarials (Antimalarial Agents)IBA 01/2019
1	OsteopontinIBA 01/2019

Therapy/Procedure

32	Therapeutics 05/2024 - 09/2005
2	Biological Therapy 12/2022 - 11/2019
2	Ambulatory Care (Outpatient Care) 01/2012 - 06/2003
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2023
1	Drug Therapy (Chemotherapy) 01/2022
1	Drug Tapering 12/2020
1	Replacement Arthroplasty 01/2019
1	Injections 01/2018