Adam Brufsky Selected Research

Histone Deacetylase Inhibitors

11/2021	Phase I Study of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors (ETCTN-9844).
6/2017	Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study.

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Adam Brufsky Research Topics

Disease

96	Breast Neoplasms (Breast Cancer) 03/2024 - 04/2005
42	Neoplasms (Cancer) 03/2024 - 04/2005
20	Neoplasm Metastasis (Metastasis) 02/2024 - 05/2006
14	Triple Negative Breast Neoplasms 02/2024 - 10/2010
5	COVID-19 01/2021 - 01/2020
5	Pain (Aches) 03/2019 - 09/2012
4	Diarrhea 02/2023 - 01/2004
4	Disease Progression 01/2023 - 04/2010
3	Fatigue 02/2024 - 01/2018
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 11/2012
3	Hypercalcemia (Milk Alkali Syndrome) 08/2015 - 05/2006
3	Prostatic Neoplasms (Prostate Cancer) 05/2006 - 07/2003
2	Circulating Neoplastic Cells 01/2023 - 12/2015
2	Ductal Carcinoma 03/2021 - 01/2010
2	Anemia 01/2021 - 01/2018
2	Neutropenia 01/2021 - 09/2008
2	Obesity 01/2021 - 07/2006
2	Pneumonia (Pneumonitis) 01/2021 - 01/2018
2	Brain Neoplasms (Brain Tumor) 01/2021 - 02/2009
2	Hyperglycemia 01/2020 - 01/2018
2	Central Nervous System Diseases (CNS Diseases) 01/2020 - 02/2009
2	Spontaneous Fractures (Pathological Fracture) 08/2015 - 05/2006
2	Bone Resorption 01/2007 - 04/2006
2	Osteoporosis 05/2006 - 04/2006
1	Residual Neoplasm 03/2023

Drug/Important Bio-Agent (IBA)

30	Hormones (Hormone)IBA 02/2024 - 08/2005
20	Aromatase InhibitorsIBA 03/2024 - 04/2006
19	palbociclibIBA 03/2024 - 10/2019
15	Diphosphonates (Bisphosphonates)IBA 01/2020 - 04/2006
14	ErbB Receptors (EGF Receptor)IBA 01/2024 - 11/2012
11	Trastuzumab (Herceptin)FDA Link 01/2022 - 01/2004
10	Estrogen ReceptorsIBA 03/2021 - 04/2006
9	Letrozole (Femara)FDA LinkGeneric 06/2023 - 04/2006
8	Biomarkers (Surrogate Marker)IBA 03/2021 - 11/2009
7	Paclitaxel (Taxol)FDA LinkGeneric 01/2023 - 04/2005
7	Zoledronic Acid (Zometa)FDA Link 01/2021 - 04/2006
5	human ERBB2 proteinIBA 02/2024 - 04/2010
5	Cyclin-Dependent Kinase 4IBA 11/2023 - 01/2021
5	Gemcitabine FDA Link 01/2021 - 01/2011
5	Bevacizumab (Avastin)FDA Link 01/2016 - 04/2009
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2010
4	AnthracyclinesIBA 01/2022 - 11/2012
4	Progesterone Receptors (Progesterone Receptor)IBA 03/2021 - 04/2006
4	Capecitabine (Xeloda)FDA Link 01/2021 - 09/2008
4	Estrogens (Estrogen)FDA Link 01/2018 - 04/2006
3	entinostat (MS 275)IBA 02/2024 - 06/2017
3	Epidermal Growth Factor (EGF)IBA 11/2023 - 03/2023
3	neratinibIBA 02/2023 - 01/2020
3	Carboplatin (JM8)FDA LinkGeneric 12/2022 - 12/2015
3	sacituzumab govitecanIBA 09/2022 - 01/2021
3	Fulvestrant (Faslodex)FDA Link 01/2021 - 04/2008
3	Lapatinib (GW572016)FDA Link 01/2020 - 02/2009
3	Denosumab FDA Link 01/2020 - 12/2010
3	taxaneIBA 08/2017 - 09/2008
3	ixabepilone (BMS 247550)FDA Link 08/2017 - 04/2005
3	130-nm albumin-bound paclitaxelIBA 01/2017 - 12/2015
3	Risedronic Acid (Actonel)FDA LinkGeneric 01/2016 - 01/2007
3	AndrogensIBA 05/2006 - 07/2003
2	Immunoconjugates (Immunoconjugate)IBA 02/2024 - 01/2021
2	Surface Antigens (Surface Antigen)IBA 02/2024 - 01/2021
2	NivolumabIBA 02/2024 - 11/2021
2	IpilimumabIBA 02/2024 - 11/2021
2	2- benzylidene- 3- (cyclohexylamino)- 2,3- dihydro- 1H- inden- 1- oneIBA 06/2023 - 10/2011
2	Tyrosine Kinase InhibitorsIBA 02/2023 - 01/2020
2	Loperamide (Imodium)FDA LinkGeneric 02/2023 - 01/2020
2	abemaciclibIBA 01/2023 - 03/2021
2	Histone Deacetylase InhibitorsIBA 11/2021 - 06/2017
2	AntibodiesIBA 03/2021 - 11/2009
2	eribulin FDA Link 01/2021 - 12/2016
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2021 - 01/2004
2	Everolimus FDA Link 01/2020 - 01/2018
2	Messenger RNA (mRNA)IBA 09/2017 - 10/2013
2	RNA (Ribonucleic Acid)IBA 09/2017 - 11/2016
2	TubulinIBA 08/2017 - 04/2005
2	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2017 - 11/2012
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/2017 - 11/2012
2	4- propionyloxy- 4- phenyl- N- methylpiperidineIBA 10/2013 - 05/2013
2	Monoclonal AntibodiesIBA 12/2010 - 10/2010
2	epothilone B (EPO906)IBA 09/2008 - 04/2005
2	Testosterone (Sustanon)FDA Link 07/2006 - 07/2003
2	Prostate-Specific Antigen (Semenogelase)IBA 05/2006 - 07/2003
1	Transaminases (Aminotransferases)IBA 02/2024
1	ostarineIBA 02/2024
1	Androgen Receptors (Androgen Receptor)IBA 02/2024
1	HM781-36BIBA 01/2024
1	TabletsIBA 10/2023
1	N-acetyltalosaminuronic acid (NAT)IBA 03/2023
1	Circulating Tumor DNAIBA 03/2023
1	TFXIBA 03/2023
1	BL 11 (BL11)IBA 02/2023
1	pertuzumabIBA 02/2023
1	AntidiarrhealsIBA 02/2023
1	(2,4- dihydroxy- 5- isopropylphenyl)- (5- (4- methylpiperazin- 1- ylmethyl)- 1,3- dihydroisoindol- 2- yl)methanoneIBA 01/2023
1	Molecular Chaperones (Chaperone, Molecular)IBA 01/2023
1	Complement System Proteins (Complement)IBA 01/2023
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2023

Therapy/Procedure

56	Therapeutics 03/2024 - 07/2003
26	Drug Therapy (Chemotherapy) 03/2024 - 08/2005
1	Neoadjuvant Therapy 03/2023
1	Duration of Therapy 02/2023