Laura D Brown Selected Research

Glucagon (Glukagon)

1/2021	Late gestation fetal hyperglucagonaemia impairs placental function and results in diminished fetal protein accretion and decreased fetal growth.
1/2016	Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep.
2/2015	Coordinated changes in hepatic amino acid metabolism and endocrine signals support hepatic glucose production during fetal hypoglycemia.
2/2008	Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep.

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Laura D Brown Research Topics

Disease

19	Placental Insufficiency 01/2023 - 07/2009
18	Fetal Growth Retardation (Intrauterine Growth Retardation) 05/2024 - 01/2009
10	Hypoxia (Hypoxemia) 01/2022 - 01/2009
7	Hypoglycemia (Reactive Hypoglycemia) 02/2015 - 12/2006
6	Hyperinsulinism (Hyperinsulinemia) 10/2020 - 12/2006
4	Insulin Resistance 01/2016 - 05/2011
3	Fetal Weight 01/2021 - 01/2021
2	Type 2 Diabetes Mellitus (MODY) 04/2024 - 05/2011
2	Necrotizing Enterocolitis 12/2014 - 01/2014
2	Acidosis 09/2009 - 01/2009
1	Body Weight (Weight, Body) 05/2024
1	Hypertrophy 01/2021
1	Patent Ductus Arteriosus 10/2018
1	Sepsis (Septicemia) 12/2014
1	Lung Diseases (Lung Disease) 12/2014
1	Malnutrition (Nutritional Deficiencies) 01/2013
1	Birth Weight (Birth Weights) 06/2012
1	Obesity 05/2011
1	Fetal Hypoxia 09/2009

Drug/Important Bio-Agent (IBA)

23	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 12/2006
19	Insulin (Novolin)FDA Link 01/2023 - 12/2006
14	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2009
12	Amino Acids FDA Link 01/2023 - 12/2006
7	Oxygen (Dioxygen)IBA 05/2024 - 10/2015
5	Lactic Acid (Lactate)FDA LinkGeneric 01/2023 - 02/2015
4	Pyruvic Acid (Pyruvate)IBA 01/2023 - 02/2015
4	Hormones (Hormone)IBA 01/2023 - 01/2017
4	Glucagon (Glukagon)FDA Link 01/2021 - 02/2008
3	CarbohydratesIBA 05/2024 - 01/2014
3	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022 - 02/2008
2	Insulin-Like Growth Factor I (IGF-1)IBA 05/2024 - 01/2021
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 01/2016
2	Leucine (L-Leucine)FDA Link 01/2021 - 12/2006
2	Muscle Proteins (Muscle Protein)IBA 11/2019 - 01/2018
2	Messenger RNA (mRNA)IBA 01/2016 - 02/2008
1	LipidsIBA 05/2024
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	CarbonIBA 10/2020
1	4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)IBA 11/2018
1	Indomethacin (Indometacin)FDA LinkGeneric 10/2018
1	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2018
1	Ibuprofen (Motrin)FDA LinkGeneric 10/2018
1	MicronutrientsIBA 12/2014
1	Ligases (Synthetase)IBA 06/2014
1	UbiquitinIBA 06/2014
1	Phosphotransferases (Kinase)IBA 01/2013
1	Dietary ProteinsIBA 01/2011
1	TOR Serine-Threonine KinasesIBA 12/2009
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 12/2009
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 12/2009
1	Essential Amino AcidsIBA 09/2009
1	RNA (Ribonucleic Acid)IBA 07/2009
1	Hypoglycemic Agents (Hypoglycemics)IBA 04/2009
1	Lysine (L-Lysine)FDA Link 04/2009
1	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 02/2008
1	Transcription Factors (Transcription Factor)IBA 02/2008
1	Liver GlycogenIBA 02/2008
1	PhosphoenolpyruvateIBA 02/2008
1	EnzymesIBA 02/2008

Therapy/Procedure

1	Therapeutics 01/2023
1	Compressed Air 01/2019
1	Catheters 01/2018