David G Brooks Selected Research

Protein Phosphatase 1

10/2009

Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.

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David G Brooks Research Topics

Disease

21	Neoplasms (Cancer) 03/2024 - 08/2002
21	Virus Diseases (Viral Diseases) 01/2021 - 02/2006
15	Infections 10/2020 - 02/2002
10	Persistent Infection 12/2021 - 11/2006
5	HIV Infections (HIV Infection) 01/2017 - 08/2002
3	Inflammation (Inflammations) 01/2022 - 01/2016
2	Neuroinflammatory Diseases 04/2019 - 01/2019
1	Chronic Hepatitis B 12/2023
1	Carcinosarcoma 01/2022
1	Diarrhea 01/2022
1	Endometrial Neoplasms (Endometrial Cancer) 01/2022
1	Melanoma (Melanoma, Malignant) 12/2019
1	Chronic Disease (Chronic Diseases) 01/2019
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2019
1	Heart Failure 11/2017
1	Myocarditis (Carditis) 11/2017
1	Bites and Stings (Sting) 12/2015
1	Splenomegaly 06/2015
1	Tuberculosis (Tuberculoses) 01/2014
1	Disease Progression 04/2013
1	Muscular Diseases (Myopathy) 10/2012
1	Rhabdomyolysis 10/2012
1	Neoplasm Metastasis (Metastasis) 10/2009
1	Adenoma (Adenomas) 10/2009
1	T-Cell Lymphoma (Lymphoma, T Cell) 10/2009
1	Barth Syndrome 11/2008
1	Angiolipoma 11/2007
1	Viremia 02/2006
1	Macular Degeneration (Age-Related Maculopathy) 06/2005
1	Atrophy 06/2005
1	Iron Overload 06/2005

Drug/Important Bio-Agent (IBA)

14	Antiviral Agents (Antivirals)IBA 01/2021 - 06/2006
10	Interferon Type IIBA 01/2022 - 04/2013
8	CytokinesIBA 04/2023 - 01/2003
8	Interleukin-10 (Interleukin 10)IBA 04/2019 - 03/2008
4	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2019
4	Transcription Factors (Transcription Factor)IBA 12/2022 - 10/2003
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2007
3	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2019
3	IronIBA 06/2005 - 04/2002
2	InterferonsIBA 12/2023 - 12/2022
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2007
2	pembrolizumabIBA 01/2021 - 01/2019
2	Immunoglobulin A (IgA)IBA 04/2019 - 01/2019
2	AntigensIBA 11/2017 - 10/2005
2	InterleukinsIBA 03/2008 - 11/2006
2	VaccinesIBA 03/2008 - 10/2005
2	RNA (Ribonucleic Acid)IBA 02/2006 - 01/2003
2	Ferritins (Ferritin)IBA 11/2003 - 04/2002
2	prostratinIBA 09/2003 - 08/2002
2	Phorbol EstersIBA 09/2003 - 08/2002
1	Interleukin-2 (IL2)IBA 12/2023
1	Interferon Regulatory Factor-2 (Interferon Regulatory Factor 2)IBA 12/2022
1	Antidepressive Agents (Antidepressants)IBA 12/2022
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2022
1	Alanine Transaminase (SGPT)IBA 01/2022
1	EnzymesIBA 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	cabozantinibIBA 01/2022
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	Tryptophan (L-Tryptophan)FDA Link 01/2022
1	Angiogenesis InhibitorsIBA 01/2022
1	NivolumabIBA 01/2022
1	Circulating Tumor DNAIBA 01/2021
1	STAT2 Transcription FactorIBA 10/2020
1	Small Interfering RNA (siRNA)IBA 12/2019
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 11/2017
1	Doxycycline (Periostat)FDA LinkGeneric 11/2017
1	CholesterolIBA 12/2015
1	Antigen-Antibody Complex (Immune Complex)IBA 02/2015
1	AcidsIBA 01/2014
1	Therapeutic UsesIBA 12/2013
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2012
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2011
1	CausticsIBA 01/2011
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 10/2009
1	beta-NaphthoflavoneIBA 10/2009
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 10/2009
1	Protein Phosphatase 1IBA 10/2009
1	PPAR deltaIBA 10/2009
1	GastrinsIBA 10/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2009
1	Matrix Metalloproteinase 7 (Matrilysin)IBA 10/2009
1	interleukin-21 (interleukin 21)IBA 06/2009
1	Cardiolipins (Cardiolipin)IBA 11/2008
1	DNA VaccinesIBA 03/2008
1	Anabolic Androgenic SteroidsIBA 11/2007
1	Androgen Receptors (Androgen Receptor)IBA 11/2007
1	ras ProteinsIBA 01/2007
1	Extracellular Matrix ProteinsIBA 01/2007
1	Interleukin-10 ReceptorsIBA 11/2006
1	Viral RNAIBA 02/2006
1	Thymidine KinaseIBA 10/2005
1	Retinaldehyde (Retinal)IBA 06/2005
1	ferric ferrocyanide (Prussian blue)FDA Link 06/2005
1	Familial apoceruloplasmin deficiencyIBA 06/2005

Therapy/Procedure

16	Therapeutics 03/2024 - 02/2002
5	Immunotherapy 03/2024 - 10/2018
1	Drug Therapy (Chemotherapy) 12/2022