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Volker Brinkmann Selected Research

Cytokines

2/2024Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection.
1/2019Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.
4/2010The adaptor molecule CARD9 is essential for tuberculosis control.
7/2003Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balance.

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Volker Brinkmann Research Topics

Disease

34Infections
01/2023 - 04/2002
16Inflammation (Inflammations)
01/2023 - 10/2003
13Multiple Sclerosis
06/2023 - 06/2002
9Tuberculosis (Tuberculoses)
02/2024 - 08/2003
5Listeriosis (Listeria Infection)
01/2017 - 04/2002
4Disease Progression
06/2023 - 04/2003
4Neoplasms (Cancer)
01/2020 - 11/2003
4Malaria
10/2019 - 05/2004
4Autoimmune Diseases (Autoimmune Disease)
05/2010 - 06/2002
3Pneumonia (Pneumonitis)
02/2024 - 03/2006
3Chronic Granulomatous Disease
01/2017 - 01/2007
3Virus Diseases (Viral Diseases)
01/2017 - 11/2009
3Ischemia
01/2011 - 10/2002
3Necrosis
02/2010 - 03/2004
3Lymphopenia (Lymphocytopenia)
12/2006 - 06/2002
2COVID-19
06/2023 - 01/2021
2Hypoxia (Hypoxemia)
01/2021 - 11/2003
2Fibrosis (Cirrhosis)
01/2019 - 01/2006
2Persistent Infection
11/2014 - 05/2003
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
09/2012 - 12/2010
2Thrombosis (Thrombus)
04/2012 - 08/2010
2Stroke (Strokes)
01/2011 - 08/2010
2Reperfusion Injury
01/2011 - 10/2002
2Eosinophilia
03/2006 - 12/2003
2Hyperplasia
03/2006 - 12/2003
1Sarcoidosis (Schaumann Disease)
02/2024
1Communicable Diseases (Infectious Diseases)
02/2024
1Severe Acute Respiratory Syndrome
06/2023
1Precancerous Conditions
01/2021
1Atrophic Gastritis
01/2021
1Granuloma
01/2020
1Myocarditis (Carditis)
01/2019
1Hemolysis
10/2018
1Carcinogenesis
09/2017
1Alzheimer Disease (Alzheimer's Disease)
01/2016
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2016

Drug/Important Bio-Agent (IBA)

29Fingolimod Hydrochloride (FTY720)FDA Link
06/2023 - 06/2002
11Sphingosine-1-Phosphate ReceptorsIBA
06/2023 - 12/2003
6Proteins (Proteins, Gene)FDA Link
01/2021 - 08/2003
6sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2016 - 06/2002
5AerosolsIBA
12/2021 - 09/2005
4CytokinesIBA
02/2024 - 07/2003
4NADPH Oxidases (NAD(P)H oxidase)IBA
01/2017 - 01/2007
4AntigensIBA
03/2006 - 01/2002
3VaccinesIBA
12/2021 - 09/2005
3Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2019 - 05/2003
3Amino AcidsFDA Link
05/2008 - 08/2004
3Interleukin-12 (IL 12)IBA
03/2008 - 07/2003
2NADP (NADPH)IBA
01/2021 - 09/2009
2Lactic Acid (Lactate)FDA LinkGeneric
01/2021 - 01/2020
2LipidsIBA
01/2021 - 08/2008
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
10/2019 - 01/2011
2ChromatinIBA
11/2017 - 09/2012
2Small Interfering RNA (siRNA)IBA
11/2012 - 03/2009
2Phosphates (Orthophosphate)IBA
02/2011 - 01/2007
2SphingosineIBA
02/2011 - 01/2007
2Therapeutic UsesIBA
01/2011 - 11/2009
2AutoantibodiesIBA
05/2010 - 06/2009
2DNA (Deoxyribonucleic Acid)IBA
05/2010 - 06/2009
2alpha-galactosylceramideIBA
05/2010 - 03/2008
2Interleukin-10 (Interleukin 10)IBA
04/2010 - 07/2003
2Reactive Oxygen Species (Oxygen Radicals)IBA
02/2010 - 01/2007
2NucleotidesIBA
10/2009 - 08/2008
2SphingolipidsIBA
03/2007 - 03/2005
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2006 - 07/2003
2Immunologic Factors (Immunomodulators)IBA
11/2006 - 12/2003
2Immunosuppressive Agents (Immunosuppressants)IBA
03/2005 - 06/2002
2Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA
10/2003 - 07/2003
1Biomarkers (Surrogate Marker)IBA
02/2024
1activin AIBA
02/2024
1Tuberculin (PPD)IBA
02/2024
1Activins (Activin)IBA
02/2024
1siponimodIBA
06/2023
1Antimicrobial PeptidesIBA
01/2023
1Adenosine Monophosphate (AMP)IBA
01/2023
1InterferonsIBA
01/2021
1Capsules (Microcapsules)IBA
01/2021
1Epidermal Growth Factor (EGF)IBA
01/2021
1Antiviral Agents (Antivirals)IBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2021
1Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA
01/2021
1AngiotensinsIBA
01/2021
1NAD (NADH)IBA
01/2021
1phthiocerol dimycocerosateIBA
01/2021
1mycofactocinIBA
01/2021
1Heme (Haem)IBA
10/2019
1MidkineIBA
01/2019
1AlbuminsIBA
10/2018
1CollagenIBA
10/2018
1Carrier Proteins (Binding Protein)IBA
10/2018
1Immunoglobulins (Immunoglobulin)IBA
10/2018
1RNA (Ribonucleic Acid)IBA
01/2018
1Transcription Factors (Transcription Factor)IBA
09/2017
1Complementary DNA (cDNA)IBA
01/2017
1Beclin-1IBA
01/2017
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2017

Therapy/Procedure

11Therapeutics
02/2024 - 02/2007
2Organ Transplantation
03/2005 - 06/2002
1Critical Care (Surgical Intensive Care)
06/2023
1Tattooing
01/2017