Gilles Brackman Selected Research

Infections

3/2017	Screening a repurposing library for potentiators of antibiotics against Staphylococcus aureus biofilms.
2/2017	Novel hamamelitannin analogues for the treatment of biofilm related MRSA infections-A scaffold hopping approach.
1/2017	Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach.
1/2017	Pitfalls associated with evaluating enzymatic quorum quenching activity: the case of MomL and its effect on Pseudomonas aeruginosa and Acinetobacter baumannii biofilms.
1/2017	Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models.
10/2016	Enrichment of enzymatically mineralized gellan gum hydrogels with phlorotannin-rich Ecklonia cava extract Seanol(®) to endow antibacterial properties and promote mineralization.
2/2016	The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release.
1/2016	Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo.
1/2016	Hamamelitannin Analogues that Modulate Quorum Sensing as Potentiators of Antibiotics against Staphylococcus aureus.
10/2015	Phenotypic characterization of an international Pseudomonas aeruginosa reference panel: strains of cystic fibrosis (CF) origin show less in vivo virulence than non-CF strains.

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Gilles Brackman Research Topics

Disease

14	Infections 03/2017 - 06/2011
3	Wounds and Injuries (Trauma) 04/2021 - 01/2013
3	Starvation 01/2011 - 09/2008
1	Allergic Contact Dermatitis 04/2021
1	Hypersensitivity (Allergy) 04/2021
1	Staphylococcal Infections 10/2016
1	Pseudomonas Infections 02/2015
1	Foreign Bodies (Foreign Body) 09/2013

Drug/Important Bio-Agent (IBA)

6	Anti-Bacterial Agents (Antibiotics)IBA 03/2017 - 09/2008
4	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 09/2008
3	Vancomycin FDA LinkGeneric 02/2017 - 10/2016
2	hamamelitanninIBA 02/2017 - 10/2016
1	ParabensIBA 04/2021
1	LigandsIBA 02/2017
1	EnzymesIBA 01/2017
1	calcium phosphateIBA 10/2016
1	SiderophoresIBA 01/2016
1	O Antigens (O Antigen)IBA 10/2015
1	AlginatesIBA 10/2015
1	PyocyanineIBA 10/2015
1	UreaseIBA 10/2015
1	Peptides (Polypeptides)IBA 02/2015
1	Amino Acids FDA Link 02/2015
1	Anti-Infective Agents (Microbicides)IBA 01/2015
1	Tobramycin (Nebcin)FDA LinkGeneric 09/2013
1	Local Anti-Infective Agents (Antiseptics)IBA 01/2013
1	cinnamaldehyde (cinnamic aldehyde)FDA Link 01/2011
1	NucleosidesIBA 12/2009

Therapy/Procedure

5	Therapeutics 03/2017 - 01/2015