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Thierry Bordet Selected Research

Motor Neuron Disease (Primary Lateral Sclerosis)

1/2010Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound.
7/2002In vivo electrotransfer of the cardiotrophin-1 gene into skeletal muscle slows down progression of motor neuron degeneration in pmn mice.

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Thierry Bordet Research Topics

Disease

3Hypoxia (Hypoxemia)
10/2022 - 06/2010
3Neurodegenerative Diseases (Neurodegenerative Disease)
12/2015 - 08/2007
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2010 - 08/2007
2Iron Overload
10/2022 - 09/2020
2Retinal Degeneration
10/2022 - 09/2020
2Inflammation (Inflammations)
10/2020 - 10/2018
2Uveitis
10/2020 - 10/2018
2Macular Degeneration (Age-Related Maculopathy)
09/2020 - 01/2019
2Mitochondrial Diseases (Mitochondrial Disease)
12/2015 - 08/2014
2Huntington Disease (Huntington's Disease)
12/2015 - 08/2014
2Reperfusion Injury
08/2015 - 06/2010
2Infarction (Infarctions)
08/2015 - 06/2010
2Starvation
08/2015 - 07/2003
2Neoplasms (Cancer)
09/2010 - 08/2008
2Spinal Muscular Atrophy (Progressive Muscular Atrophy)
04/2010 - 01/2010
2Motor Neuron Disease (Primary Lateral Sclerosis)
01/2010 - 07/2002
2Neuralgia (Stump Neuralgia)
12/2009 - 08/2008
2Hyperalgesia
12/2009 - 08/2008
2Peripheral Nervous System Diseases (PNS Diseases)
12/2009 - 08/2008
2Pain (Aches)
10/2009 - 08/2008
1Glaucoma
10/2022
1Ocular Hypertension (Glaucoma, Suspect)
10/2022
1Retinitis Pigmentosa (Pigmentary Retinopathy)
09/2020
1Retinal Diseases
01/2019
1Blindness (Hysterical Blindness)
10/2018
1Necrosis
01/2018
1Pancreatitis
01/2018
1Cerebral Cortical Thinning
12/2015
1Hypothermia
08/2015
1Parkinsonian Disorders (Parkinsonism)
09/2014
1Demyelinating Diseases (Demyelinating Disease)
02/2012
1Neuroblastoma
09/2010
1Glioblastoma (Glioblastoma Multiforme)
09/2010
1Myocardial Ischemia (Ischemic Heart Diseases)
06/2010
1Myocardial Infarction
06/2010
1Respiratory Insufficiency (Respiratory Failure)
04/2010
1Paralysis (Palsy)
04/2010
1Acute Pain
10/2009
1Painful Neuropathy
08/2008
1Acute Liver Failure (Fulminant Hepatic Failure)
07/2003
1Inborn Genetic Diseases (Disease, Hereditary)
07/2002

Drug/Important Bio-Agent (IBA)

9olesoximeIBA
12/2015 - 08/2007
4Proteins (Proteins, Gene)FDA Link
01/2019 - 04/2010
43,5-seco-4-norcholestan-5-one oxime-3-olIBA
01/2018 - 06/2010
3CholesterolIBA
09/2014 - 08/2008
3Analgesics (Analgesic Drugs)IBA
12/2009 - 08/2008
2Neuroprotective AgentsIBA
10/2022 - 12/2009
2Retinaldehyde (Retinal)IBA
10/2022 - 09/2020
2IronIBA
10/2022 - 09/2020
2Transferrin (beta 2 Transferrin)IBA
10/2022 - 09/2020
2Therapeutic UsesIBA
10/2020 - 07/2002
2Mitochondrial Permeability Transition PoreIBA
01/2018 - 06/2010
2CalciumIBA
12/2015 - 06/2010
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
08/2015 - 06/2010
2OximesIBA
09/2014 - 12/2009
2Vincristine (Oncovin)FDA LinkGeneric
12/2009 - 08/2008
1N-Methylaspartate (NMDA)IBA
10/2022
1EndotoxinsIBA
10/2018
1EstersIBA
01/2018
1palmitoleic acidIBA
01/2018
1Fatty Acids (Saturated Fatty Acids)IBA
01/2018
1CalpainIBA
12/2015
1Huntingtin ProteinIBA
12/2015
1Peptide Hydrolases (Proteases)FDA Link
12/2015
1AnionsIBA
08/2015
1mitoquinoneIBA
08/2015
1Superoxides (Superoxide)IBA
08/2015
1alpha-SynucleinIBA
09/2014
1Pemetrexed (MTA)FDA Link
09/2010
1Cyclosporine (Ciclosporin)FDA LinkGeneric
06/2010
1Apoptosis Inducing FactorIBA
06/2010
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
06/2010
1Paclitaxel (Taxol)FDA LinkGeneric
12/2009
1Mitochondrial Proteins (Mitochondrial Protein)IBA
12/2009
1Streptozocin (Streptozotocin)FDA Link
08/2008
1Formaldehyde (Formol)FDA Link
08/2008
1CytokinesIBA
07/2003
1Transforming Growth Factor beta (TGF-beta)IBA
07/2003

Therapy/Procedure

6Therapeutics
10/2020 - 08/2008
1Drug Therapy (Chemotherapy)
08/2008
1Oral Administration
08/2008
1Hepatectomy
07/2003
1Intramuscular Injections
07/2002