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Graeme I Bell Selected Research

Proteins (Proteins, Gene)

6/2014Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.
10/2012Localization of hepatocyte nuclear factor-4α in the nucleolus and nucleus is regulated by its C-terminus.
9/2010Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.
3/2010In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.
1/2010Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted.
6/2006From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
9/2002Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.

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Graeme I Bell Research Topics

Disease

24Type 2 Diabetes Mellitus (MODY)
01/2017 - 04/2002
8Insulin Resistance
01/2017 - 01/2002
6Insulinoma
01/2017 - 04/2008
4Diabetes Mellitus
08/2010 - 03/2002
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
05/2012 - 04/2008
3Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
12/2009 - 09/2002
3Hyperglycemia
08/2009 - 06/2006
3Mason-Type Diabetes
04/2008 - 11/2003
2Ketosis
06/2011 - 04/2008
2Body Weight (Weight, Body)
05/2010 - 01/2003
2Obesity
12/2009 - 03/2002
1Hypertriglyceridemia
06/2015
1Inflammation (Inflammations)
06/2015
1Glucose Intolerance
03/2015
1Type 3 Maturity-Onset Diabetes of the Young
06/2014
1Seizures (Absence Seizure)
05/2014
1Microcephaly
05/2014
1Autoimmune Diseases (Autoimmune Disease)
09/2010
1Permanent Neonatal Diabetes Mellitus
03/2010
1Hyperproinsulinemia
01/2010
1Diabetic Retinopathy (Retinopathy, Diabetic)
01/2010
1Diabetic Ketoacidosis (Ketoacidosis, Diabetic)
09/2007
1Type 2 Maturity-Onset Diabetes of the Young
06/2006
11 Noninsulin-Dependent Diabetes Mellitus
02/2004
1Diabetic Nephropathies (Diabetic Nephropathy)
11/2003
1Hyperlipidemias (Hyperlipidemia)
11/2003
1Urogenital Abnormalities
11/2003
1Coronary Disease (Coronary Heart Disease)
11/2003
1Familial Combined Hyperlipidemia (Combined Hyperlipidemia, Familial)
11/2003
1Genetic Predisposition to Disease (Genetic Predisposition)
05/2003
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
03/2003
1Atherosclerosis
03/2003
1Cholesteryl Ester Transfer Protein Deficiency
03/2003

Drug/Important Bio-Agent (IBA)

12Insulin (Novolin)FDA Link
01/2017 - 01/2002
10Glucose (Dextrose)FDA LinkGeneric
03/2015 - 01/2002
7Proteins (Proteins, Gene)FDA Link
06/2014 - 09/2002
4DNA (Deoxyribonucleic Acid)IBA
06/2014 - 01/2002
3ProinsulinIBA
01/2017 - 01/2010
3Blood Glucose (Blood Sugar)IBA
05/2012 - 01/2003
3AutoantibodiesIBA
06/2011 - 09/2007
3Cysteine Proteases (Cysteine Protease)IBA
01/2005 - 04/2002
2LipidsIBA
06/2015 - 11/2003
2Complement System Proteins (Complement)IBA
01/2012 - 05/2010
2C-PeptideIBA
06/2011 - 12/2002
2Triglycerides (Triacylglycerol)IBA
05/2010 - 11/2003
2Mutant Proteins (Protein, Mutant)IBA
01/2010 - 02/2004
2CholesterolIBA
10/2004 - 11/2003
2CalpainIBA
02/2004 - 05/2003
2Hepatocyte Nuclear FactorsIBA
11/2003 - 03/2002
1LactonesIBA
06/2015
1galactonic acidIBA
06/2015
1Arachidonic Acid (Vitamin F)IBA
06/2015
1EicosanoidsIBA
06/2015
1threonic acid (threonate)IBA
06/2015
1Cysteine (L-Cysteine)FDA Link
06/2015
1Phosphatidylcholines (Phosphatidylcholine)IBA
06/2015
1Methionine (L-Methionine)FDA Link
06/2015
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
06/2015
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
06/2015
1Hepatocyte Nuclear Factor 1IBA
06/2014
1Tacrolimus (Prograf)FDA LinkGeneric
01/2013
1Sirolimus (Rapamycin)FDA Link
01/2013
1alogliptinIBA
01/2013
1Pioglitazone (Actos)FDA Link
01/2013
1HLA Antigens (Human Leukocyte Antigens)IBA
06/2011
1AntigensIBA
06/2011
1Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA
06/2011
1AntibodiesIBA
06/2011
1LeptinIBA
05/2010
1Nonesterified Fatty Acids (NEFA)IBA
05/2010
1IncretinsIBA
02/2010
1ForminsIBA
01/2010
1Calcium-Calmodulin-Dependent Protein Kinase Type 4IBA
01/2010
1Perilipin-1IBA
12/2009
1Adenosine Triphosphate (ATP)IBA
08/2009
1Dihydrotachysterol (AT 10)IBA
04/2008
1GlucokinaseIBA
06/2006
1ginsenoside ReIBA
06/2005
1HDL-triglycerideIBA
10/2004
1Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
06/2004
1Protein Phosphatase 1IBA
06/2004
1ElementsIBA
06/2004
1GlycogenIBA
06/2004
1Glycogen Synthase (Synthase I)IBA
06/2004
1calpastatinIBA
05/2004
1Peptide Hydrolases (Proteases)FDA Link
02/2004
12,5- dibromo- 2- (beta- naphthyl)indan- 1,3- dioneIBA
02/2004
1calpain 10IBA
02/2004
1Lipoproteins (Lipoprotein)IBA
11/2003
1Hepatocyte Nuclear Factor 1-betaIBA
11/2003
1calpain inhibitorsIBA
05/2003
1HDL CholesterolIBA
03/2003
1AndrogensIBA
09/2002
1Insulin Receptor Substrate ProteinsIBA
09/2002
1Insulin ReceptorIBA
09/2002

Therapy/Procedure

2Therapeutics
01/2014 - 01/2013
1Precision Medicine
08/2010