Djahida Bedja Selected Research

Myocarditis (Carditis)

1/2017	Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy.
10/2013	Fatal eosinophilic myocarditis develops in the absence of IFN-γ and IL-17A.
2/2013	TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4.
5/2012	IL-33 independently induces eosinophilic pericarditis and cardiac dilation: ST2 improves cardiac function.
4/2012	Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n.
1/2012	Th2 regulation of viral myocarditis in mice: different roles for TLR3 versus TRIF in progression to chronic disease.
5/2010	Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy.
5/2008	Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation.

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Djahida Bedja Research Topics

Disease

16	Heart Failure 01/2023 - 10/2003
14	Hypertrophy 12/2020 - 02/2005
11	Fibrosis (Cirrhosis) 10/2019 - 05/2008
11	Heart Diseases (Heart Disease) 01/2019 - 01/2012
10	Cardiomegaly (Heart Hypertrophy) 12/2020 - 02/2005
8	Myocarditis (Carditis) 01/2017 - 05/2008
7	Marfan Syndrome (Marfan's Syndrome) 01/2019 - 12/2004
7	Neoplasms (Cancer) 03/2016 - 02/2007
6	Inflammation (Inflammations) 01/2018 - 05/2008
6	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2017 - 05/2008
6	Cardiomyopathies (Cardiomyopathy) 04/2016 - 09/2006
5	Aneurysm (Aneurysms) 01/2019 - 04/2011
5	Atherosclerosis 01/2018 - 01/2008
5	Cardiotoxicity 07/2014 - 10/2003
4	Myocardial Infarction 12/2020 - 09/2006
3	Necrosis 01/2021 - 04/2008
3	Obesity 09/2019 - 03/2006
3	Infarction (Infarctions) 11/2018 - 09/2006
3	Aortic Aneurysm (Aneurysm, Aortic) 10/2015 - 04/2006
3	Cardiovascular Diseases (Cardiovascular Disease) 03/2015 - 01/2008
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 07/2010
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019 - 11/2018
2	Loeys-Dietz Syndrome 01/2019 - 01/2014
2	Aortic Dissection 01/2019 - 10/2015
2	Reperfusion Injury 01/2019 - 11/2018
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 12/2017 - 02/2014
2	Thoracic Aortic Aneurysm 01/2017 - 10/2015
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2016 - 01/2012
2	Infections 02/2013 - 02/2011
2	Autoimmune Diseases (Autoimmune Disease) 05/2012 - 05/2010
2	Ischemia 03/2012 - 04/2008
2	Hypertension (High Blood Pressure) 12/2011 - 04/2006
2	Atherosclerotic Plaque (Atheroma) 04/2010 - 01/2008
2	Neoplasm Metastasis (Metastasis) 09/2008 - 03/2007
2	Pancreatic Neoplasms (Pancreatic Cancer) 09/2008 - 03/2007
1	Ventricular Remodeling 12/2020
1	Body Weight (Weight, Body) 01/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020

Drug/Important Bio-Agent (IBA)

7	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2022 - 02/2005
7	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2011
6	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 01/2022 - 01/2009
6	Nitric Oxide Synthase (NO Synthase)IBA 03/2016 - 04/2008
6	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2016 - 10/2003
5	CytokinesIBA 10/2019 - 05/2010
5	Apolipoproteins E (ApoE)IBA 01/2018 - 01/2008
4	Peptides (Polypeptides)IBA 01/2021 - 05/2008
4	Phosphotransferases (Kinase)IBA 12/2020 - 04/2009
4	GlycosphingolipidsIBA 01/2020 - 06/2014
4	Angiotensin IIIBA 01/2019 - 04/2011
4	CholesterolIBA 01/2018 - 02/2011
4	Fibrillin-1IBA 01/2017 - 12/2004
4	Interleukin-4 (Interleukin 4)IBA 01/2017 - 05/2008
4	InterleukinsIBA 03/2012 - 05/2008
4	Sildenafil Citrate (Viagra)FDA Link 12/2010 - 02/2005
3	TRPC6 Cation ChannelIBA 01/2019 - 02/2014
3	CalciumIBA 01/2019 - 01/2009
3	Antineoplastic Agents (Antineoplastics)IBA 03/2016 - 10/2003
3	Adrenergic Agents (Adrenergic Drugs)IBA 03/2016 - 11/2009
3	Losartan (Cozaar)FDA LinkGeneric 05/2015 - 04/2006
3	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 03/2015 - 01/2009
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014 - 01/2010
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2014 - 01/2010
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2023 - 09/2019
2	Streptozocin (Streptozotocin)FDA Link 01/2020 - 07/2010
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2020 - 01/2019
2	TOR Serine-Threonine KinasesIBA 01/2020 - 01/2020
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2019 - 01/2014
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019 - 04/2011
2	MicroRNAs (MicroRNA)IBA 01/2018 - 01/2014
2	DystrophinIBA 12/2017 - 02/2014
2	sapropterin (tetrahydrobiopterin)FDA Link 03/2016 - 05/2008
2	ErbB Receptors (EGF Receptor)IBA 01/2016 - 01/2012
2	Insulin (Novolin)FDA Link 10/2015 - 07/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2015 - 08/2012
2	Oxidants (Oxidizing Agents)IBA 07/2014 - 05/2008
2	ApolipoproteinsIBA 06/2014 - 04/2010
2	Monoamine Oxidase (MAO)IBA 01/2014 - 01/2010
2	Adenosine Triphosphate (ATP)IBA 01/2014 - 04/2008
2	Cardiac MyosinsIBA 10/2013 - 05/2008
2	Interleukin-17 (Interleukin 17)IBA 10/2013 - 05/2010
2	Interleukin-10 (Interleukin 10)IBA 02/2013 - 03/2012
2	Interleukin-33IBA 05/2012 - 01/2012
2	Interleukin-6 (Interleukin 6)IBA 05/2012 - 03/2012
2	Scavenger Receptors (Scavenger Receptor)IBA 02/2011 - 01/2008
2	Cyclic GMPIBA 02/2009 - 02/2005
2	CalcineurinIBA 02/2009 - 02/2005
2	cyclopamineIBA 09/2008 - 03/2007
2	AntioxidantsIBA 05/2008 - 01/2008
2	Transforming Growth Factor beta (TGF-beta)IBA 04/2006 - 12/2004
1	calpastatinIBA 01/2021
1	Cyclophilin AIBA 01/2021
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 12/2020
1	entinostat (MS 275)IBA 12/2020
1	Small Interfering RNA (siRNA)IBA 12/2020
1	RGFP966IBA 12/2020
1	apicidinIBA 12/2020
1	Histone Deacetylases (Histone Deacetylase)IBA 12/2020
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 12/2020
1	quisinostatIBA 12/2020

Therapy/Procedure

10	Therapeutics 03/2016 - 09/2006