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Katrina K Bakken Selected Research

Therapeutics

1/2021In Vivo Efficacy of Tesevatinib in EGFR-Amplified Patient-Derived Xenograft Glioblastoma Models May Be Limited by Tissue Binding and Compensatory Signaling.
1/2021Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks.
12/2017Restricted Delivery of Talazoparib Across the Blood-Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma.
5/2016Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma.
7/2014Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.

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Katrina K Bakken Research Topics

Disease

11Neoplasms (Cancer)
02/2024 - 07/2014
11Glioblastoma (Glioblastoma Multiforme)
02/2024 - 07/2014
2Brain Neoplasms (Brain Tumor)
01/2024 - 04/2015
1Melanoma (Melanoma, Malignant)
01/2024
1Neoplasm Metastasis (Metastasis)
01/2024
1Lung Neoplasms (Lung Cancer)
01/2021
1Breast Neoplasms (Breast Cancer)
01/2021

Drug/Important Bio-Agent (IBA)

4Temozolomide (Temodar)FDA LinkGeneric
12/2017 - 07/2014
3Phosphotransferases (Kinase)IBA
01/2021 - 01/2016
2Radiation-Sensitizing AgentsIBA
02/2024 - 01/2024
2Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2017 - 07/2014
2veliparibIBA
05/2016 - 07/2014
2adavosertibIBA
01/2016 - 04/2015
1AZD1390IBA
02/2024
1galantide (M 15)IBA
01/2024
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2024
1DNA (Deoxyribonucleic Acid)IBA
01/2024
1peposertibIBA
01/2024
1ErbB Receptors (EGF Receptor)IBA
01/2023
1Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2023
1Proteins (Proteins, Gene)FDA Link
01/2023
1lisavanbulinIBA
12/2022
1depatuxizumab mafodotinIBA
01/2022
1Immunoconjugates (Immunoconjugate)IBA
01/2022
1XL647IBA
01/2021
1Tyrosine (L-Tyrosine)FDA Link
01/2021
1PhosphotyrosineIBA
01/2021
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2017
1talazoparibIBA
12/2017
1ponatinibIBA
11/2017
1Biomarkers (Surrogate Marker)IBA
05/2016

Therapy/Procedure

5Therapeutics
01/2021 - 07/2014