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J C Ashton Selected Research

Neoplasms (Cancer)

1/2021The effect of metformin in EML4-ALK+ lung cancer alone and in combination with crizotinib in cell and rodent models.
1/2020Inhibition of Mitogen-Activated Protein Kinase Kinase Alone and in Combination with Anaplastic Lymphoma Kinase (ALK) Inhibition Suppresses Tumor Growth in a Mouse Model of ALK-Positive Lung Cancer.

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J C Ashton Research Topics

Disease

4Lung Neoplasms (Lung Cancer)
01/2023 - 12/2019
2Neoplasms (Cancer)
01/2021 - 01/2020
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 12/2019
1Ischemia
05/2014
1Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
05/2014
1Neuroinflammatory Diseases
05/2014
1Hypoxia (Hypoxemia)
05/2014
1Neuralgia (Stump Neuralgia)
02/2012
1Pain (Aches)
02/2012
1Hyperalgesia
02/2012

Drug/Important Bio-Agent (IBA)

3CrizotinibIBA
01/2021 - 12/2019
3Anaplastic Lymphoma KinaseIBA
01/2021 - 12/2019
2AZD 6244IBA
01/2020 - 12/2019
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2020 - 12/2019
21- (2,3- dichlorobenzoyl)- 5- methoxy- 2- methyl- (2- (mopholin- 4- yl)ethyl)- 1H- indoleIBA
05/2014 - 02/2012
2CannabinoidsIBA
05/2014 - 02/2012
2CB2 Cannabinoid ReceptorIBA
05/2014 - 02/2012
1SHP099IBA
01/2023
1alectinibIBA
01/2023
1Metformin (Glucophage)FDA LinkGeneric
01/2021
1Insulin (Novolin)FDA Link
01/2021
1Insulin-Like Growth Factor I (IGF-1)IBA
01/2021
1Drug CombinationsIBA
01/2020
1Tyrosine Kinase InhibitorsIBA
12/2019
11,1-dimethylbutyl-1-deoxy-Delta(9)-THCIBA
02/2012

Therapy/Procedure

1Therapeutics
01/2020