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Bernd Arnold Selected Research

Matrix Metalloproteinases (MMPs)

1/2017Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.
5/2011Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease.
9/2009Altered apoptosis of inflammatory neutrophils in MMP-9-deficient mice is due to lower expression and activity of caspase-3.
9/2009Increased cyclooxygenase activity impairs apoptosis of inflammatory neutrophils in mice lacking gelatinase B/matrix metalloproteinase-9.
3/2009Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis.
1/2008Gelatinase B/MMP-9 as an inflammatory marker enzyme in mouse zymosan peritonitis: comparison of phase-specific and cell-specific production by mast cells, macrophages and neutrophils.
7/2006Enhanced early vascular permeability in gelatinase B (MMP-9)-deficient mice: putative contribution of COX-1-derived PGE2 of macrophage origin.
4/2003Central role of RAGE-dependent neointimal expansion in arterial restenosis.

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Bernd Arnold Research Topics

Disease

17Neoplasms (Cancer)
03/2015 - 03/2002
15Inflammation (Inflammations)
01/2016 - 03/2002
8Peritonitis
11/2009 - 01/2006
5Carcinogenesis
08/2014 - 12/2005
4Lymphopenia (Lymphocytopenia)
03/2010 - 09/2002
3Neoplasm Metastasis (Metastasis)
03/2015 - 06/2011
3Hepatocellular Carcinoma (Hepatoma)
08/2014 - 03/2009
3Autoimmune Diseases (Autoimmune Disease)
05/2011 - 10/2003
3Septic Shock (Toxic Shock Syndrome)
11/2005 - 08/2002
2Fibrosis (Cirrhosis)
01/2016 - 02/2011
2Melanoma (Melanoma, Malignant)
03/2015 - 06/2011
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
10/2012 - 01/2006
2Multiple Sclerosis
11/2008 - 01/2006
2Chronic Disease (Chronic Diseases)
11/2005 - 06/2005
2Sepsis (Septicemia)
06/2004 - 08/2002
1Autistic Disorder (Autism)
11/2020
1Atrophy
01/2018
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2018
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2017
1Colitis
01/2017
1Hemochromatosis (Bronze Diabetes)
01/2017
1Iron Overload
01/2017
1Breast Neoplasms (Breast Cancer)
05/2016
1Eosinophilia
01/2016
1Neuralgia (Stump Neuralgia)
05/2015
1Pain (Aches)
05/2015
1Adenocarcinoma
03/2015
1Hepatitis
08/2014
1Hypersensitivity (Allergy)
07/2013
1Infections
09/2012
1Hyperplasia
01/2012
1Autoimmune Lymphoproliferative Syndrome
05/2011
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2011
1Lymphadenopathy
05/2011
1Splenomegaly
05/2011
1Alzheimer Disease (Alzheimer's Disease)
02/2010

Drug/Important Bio-Agent (IBA)

10Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2017 - 08/2002
9LigandsIBA
05/2016 - 05/2003
9ZymosanIBA
06/2010 - 01/2006
8Matrix Metalloproteinases (MMPs)IBA
01/2017 - 04/2003
7Proteins (Proteins, Gene)FDA Link
01/2016 - 06/2005
6Receptor for Advanced Glycation End ProductsIBA
07/2013 - 04/2003
5Peptides (Polypeptides)IBA
01/2017 - 01/2006
4AntigensIBA
09/2012 - 03/2002
3AutoantigensIBA
10/2012 - 01/2006
3Messenger RNA (mRNA)IBA
11/2009 - 03/2009
3Advanced Glycation End ProductsIBA
11/2005 - 05/2003
2Leukocyte Elastase (Neutrophil Elastase)IBA
05/2015 - 03/2009
2AntibodiesIBA
03/2015 - 05/2008
2Sorafenib (BAY 43-9006)FDA Link
08/2014 - 10/2013
2Cre recombinaseIBA
08/2014 - 03/2009
2Interleukin-7 (Interleukin 7)IBA
01/2012 - 01/2004
2Matrix Metalloproteinase InhibitorsIBA
05/2011 - 01/2008
2Toll-Like Receptors (Toll-Like Receptor)IBA
03/2010 - 03/2009
2Protein Isoforms (Isoforms)IBA
11/2009 - 09/2009
2Prostaglandins EIBA
11/2009 - 09/2009
2Prostaglandins DIBA
11/2009 - 09/2009
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
11/2009 - 09/2009
2EnzymesIBA
01/2008 - 08/2002
2ChemokinesIBA
01/2006 - 12/2005
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2005 - 04/2003
2Amyloid beta-PeptidesIBA
11/2005 - 07/2003
2HMGB1 Protein (HMG1)IBA
06/2005 - 06/2005
2CPG-oligonucleotideIBA
05/2004 - 12/2002
1Glutamic Acid (Glutamate)FDA Link
11/2020
1Imiquimod (Aldara)FDA LinkGeneric
01/2018
1Actin Depolymerizing Factors (Cofilins)IBA
01/2018
1SodiumIBA
01/2017
1HepcidinsIBA
01/2017
1IronIBA
01/2017
1AcidsIBA
01/2017
1Dextrans (Dextran)FDA Link
01/2017
1OvalbuminIBA
01/2016
1Glycoproteins (Glycoprotein)IBA
01/2016
1CytokinesIBA
01/2016
1InterferonsIBA
01/2016
1salicylhydroxamic acid (SHAM)IBA
05/2015
1Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
05/2015
1SerpinsIBA
05/2015
1Epidermal Growth Factor (EGF)IBA
03/2015
1Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
03/2015
1Tumor Viral Antigens (Large T Antigen)IBA
08/2014
1AlbuminsIBA
08/2014
1RNA (Ribonucleic Acid)IBA
06/2014
1Pattern Recognition ReceptorsIBA
07/2013
1Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA
07/2013
1Junctional Adhesion Molecule CIBA
06/2011
1AutoantibodiesIBA
05/2011
1Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2010
1Interleukin-15 (Interleukin 15)IBA
03/2010
1Interferon gamma ReceptorIBA
03/2010
13 (or 17)-beta-hydroxysteroid dehydrogenaseIBA
02/2010
1ProstaglandinsIBA
11/2009

Therapy/Procedure

9Therapeutics
05/2015 - 03/2002
3Ligation
10/2012 - 06/2004
2Transplantation
01/2015 - 03/2009
2Immunotherapy
05/2008 - 05/2004
2Punctures
11/2005 - 06/2004
1Kidney Transplantation
02/2011