John Arcaroli Selected Research

Lung Injury

2/2008	Association between urokinase haplotypes and outcome from infection-associated acute lung injury.
6/2003	Urokinase-type plasminogen activator potentiates lipopolysaccharide-induced neutrophil activation.
4/2003	Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury.
4/2003	Activation of gene expression in human neutrophils by high mobility group box 1 protein.

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John Arcaroli Research Topics

Disease

8	Neoplasms (Cancer) 01/2017 - 08/2012
5	Acute Lung Injury 02/2008 - 09/2002
4	Lung Injury 02/2008 - 04/2003
4	Sepsis (Septicemia) 10/2007 - 04/2003
3	Colorectal Neoplasms (Colorectal Cancer) 11/2017 - 04/2013
3	Pancreatic Neoplasms (Pancreatic Cancer) 08/2014 - 08/2012
3	Hemorrhage 09/2004 - 09/2002
3	Endotoxemia 06/2003 - 09/2002
1	Neoplasm Metastasis (Metastasis) 01/2016
1	Carcinogenesis 01/2015
1	Colonic Neoplasms (Colon Cancer) 01/2015
1	Adenocarcinoma 08/2014
1	Adenocarcinoma of Lung 07/2013
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2013
1	Infections 02/2008
1	Shock 06/2006
1	Pulmonary Edema 06/2003
1	Inflammation (Inflammations) 04/2003

Drug/Important Bio-Agent (IBA)

4	NF-kappa B (NF-kB)IBA 10/2007 - 04/2003
3	Biomarkers (Surrogate Marker)IBA 11/2017 - 10/2012
3	Proteins (Proteins, Gene)FDA Link 10/2012 - 09/2004
2	Messenger RNA (mRNA)IBA 01/2015 - 09/2004
2	CateninsIBA 01/2015 - 07/2013
2	HMGB1 Protein (HMG1)IBA 10/2007 - 04/2003
2	CytokinesIBA 10/2005 - 06/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2004 - 06/2003
1	Aldehyde DehydrogenaseIBA 11/2017
1	Dasatinib (BMS 354825)FDA Link 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2015
1	TCF Transcription FactorsIBA 01/2015
1	Small Interfering RNA (siRNA)IBA 01/2015
1	LuciferasesIBA 01/2015
1	EnzymesIBA 08/2014
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 08/2014
1	2,2- dimethyl- N- (6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- N'- (2,2,3,3,3- pentafluoropropyl)malonamideIBA 08/2014
1	MicroRNAs (MicroRNA)IBA 07/2013
1	Cetuximab (Erbitux)FDA Link 04/2013
1	Sorafenib (BAY 43-9006)FDA Link 04/2013
1	Irinotecan (Camptosar)FDA LinkGeneric 04/2013
1	Leucine (L-Leucine)FDA Link 10/2012
1	saracatinibIBA 10/2012
1	Insulin-Like Growth Factor Binding Protein 2IBA 10/2012
1	src-Family KinasesIBA 10/2012
1	temsirolimus FDA Link 08/2012
1	N-(1,4,8,11- tetraazacyclotetradecanyl- 1,4- phenylenebis(methylene))- 2- (aminomethyl)- pyridineIBA 08/2012
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 08/2012
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 02/2008
1	Interleukin-1 Receptor-Associated KinasesIBA 06/2006
1	Toll-Like Receptors (Toll-Like Receptor)IBA 10/2005
1	Blood Coagulation Factors (Coagulation Factor)IBA 10/2005
1	EndotoxinsIBA 09/2004
1	Interleukin-1beta (Interleukin 1 beta)IBA 06/2003
1	Superoxides (Superoxide)IBA 04/2003
1	Peroxidase (Myeloperoxidase)IBA 04/2003
1	PorphyrinsIBA 04/2003
1	AEOL 10150IBA 04/2003
1	Superoxide DismutaseIBA 04/2003
1	ManganeseIBA 04/2003
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 09/2002
1	Phosphotransferases (Kinase)IBA 09/2002
1	CatecholaminesIBA 09/2002
1	Adrenergic alpha-Agonists (Adrenergic alpha-Agonist)IBA 09/2002
1	Adrenergic Agents (Adrenergic Drugs)IBA 09/2002

Therapy/Procedure

3	Therapeutics 01/2016 - 08/2012
1	Subcutaneous Injections 01/2016
1	Immunotherapy 01/2016
1	Mechanical Ventilators (Ventilator) 06/2006