Mehmet Altan Selected Research

Cytokines

1/2023	First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1).
1/2019	Role of Radiation Therapy in Modulation of the Tumor Stroma and Microenvironment.

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Mehmet Altan Research Topics

Disease

49	Neoplasms (Cancer) 12/2023 - 11/2011
27	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2024 - 09/2017
12	Colitis 08/2023 - 01/2019
11	Pneumonia (Pneumonitis) 11/2023 - 01/2022
7	Lung Neoplasms (Lung Cancer) 06/2023 - 01/2017
6	Diarrhea 08/2023 - 01/2019
6	Breast Neoplasms (Breast Cancer) 01/2018 - 04/2005
4	Autoimmune Diseases (Autoimmune Disease) 08/2023 - 01/2018
3	Hepatitis 01/2023 - 11/2022
2	Enterocolitis 08/2023 - 01/2023
2	Diverticulitis 08/2023 - 07/2023
2	Microscopic Colitis 07/2023 - 01/2020
2	Disease Progression 06/2023 - 01/2020
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023 - 01/2022
2	Cardiotoxicity 01/2023 - 01/2019
2	Myocarditis (Carditis) 01/2023 - 11/2022
2	Inflammation (Inflammations) 01/2023 - 01/2020
2	Exanthema (Rash) 01/2022 - 01/2020
2	Infections 01/2021 - 02/2015
2	Basal Cell Carcinoma (Rodent Ulcer) 07/2019 - 01/2019
2	Carcinoma (Carcinomatosis) 01/2019 - 09/2017
2	Adenocarcinoma of Lung 01/2017 - 11/2016
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2024
1	Lung Diseases (Lung Disease) 11/2023
1	Appendicitis 08/2023
1	Melanoma (Melanoma, Malignant) 08/2023
1	Colonic Diverticulitis 07/2023
1	Asthma (Bronchial Asthma) 05/2023
1	Sarcoidosis (Schaumann Disease) 05/2023
1	Reperfusion Injury 03/2023
1	Adenoid Cystic Carcinoma (Cylindroma) 01/2023
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2023
1	Mesothelioma 01/2023
1	Neoplasm Metastasis (Metastasis) 01/2023
1	Vasculitis (Vasculitides) 01/2023
1	Pleural Effusion (Pleural Effusions) 01/2023
1	Fibrosis (Cirrhosis) 01/2023
1	Cardiomegaly (Heart Hypertrophy) 01/2023
1	Acute Kidney Injury (Acute Renal Failure) 01/2023

Drug/Important Bio-Agent (IBA)

36	Immune Checkpoint InhibitorsIBA 02/2024 - 01/2018
7	pembrolizumabIBA 05/2023 - 01/2020
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2016
5	NivolumabIBA 01/2023 - 01/2021
4	SteroidsIBA 08/2023 - 01/2019
4	Anti-Bacterial Agents (Antibiotics)IBA 07/2023 - 01/2019
4	IpilimumabIBA 01/2023 - 01/2021
4	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2018
4	B7-H1 AntigenIBA 01/2019 - 08/2017
3	Immunosuppressive Agents (Immunosuppressants)IBA 07/2023 - 01/2021
3	Tyrosine Kinase InhibitorsIBA 07/2023 - 01/2018
3	AntibodiesIBA 01/2023 - 02/2015
3	durvalumabIBA 01/2023 - 09/2022
2	Circulating Tumor DNAIBA 04/2024 - 01/2021
2	vedolizumabIBA 07/2023 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2023 - 01/2017
2	Monoclonal AntibodiesIBA 01/2023 - 02/2015
2	anti-thyroglobulinIBA 01/2023 - 01/2023
2	Immunoglobulin G (IgG)IBA 01/2023 - 01/2023
2	CytokinesIBA 01/2023 - 01/2019
2	HM781-36BIBA 11/2022 - 01/2022
2	taxaneIBA 01/2020 - 01/2018
2	HhAntag691IBA 07/2019 - 01/2019
2	ErbB Receptors (EGF Receptor)IBA 01/2018 - 02/2015
1	cemiplimabIBA 04/2024
1	Docetaxel (Taxotere)FDA Link 02/2024
1	RamucirumabIBA 02/2024
1	PlatinumIBA 02/2024
1	RNA (Ribonucleic Acid)IBA 09/2023
1	1- (1- (imidazo(1,2- a)pyridin- 6- yl)ethyl)- 6- (1- methyl- 1H- pyrazol- 4- yl)- 1H- (1,2,3)triazolo(4,5- b)pyrazineIBA 08/2023
1	osimertinibIBA 08/2023
1	capmatinibIBA 08/2023
1	tepotinibIBA 08/2023
1	CrizotinibIBA 08/2023
1	Transaminases (Aminotransferases)IBA 08/2023
1	Phenobarbital (Luminal)FDA Link 08/2023
1	AntidiarrhealsIBA 07/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2023
1	Fluoxetine (Prozac)FDA LinkGeneric 03/2023
1	MicroRNAs (MicroRNA)IBA 01/2023
1	Iodide Peroxidase (Deiodinase)IBA 01/2023
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2023
1	Complement System Proteins (Complement)IBA 01/2023
1	Troponin IIBA 01/2023
1	Axitinib (AG 013736)IBA 01/2023
1	TroponinIBA 01/2023
1	Peptides (Polypeptides)IBA 01/2023
1	avelumabIBA 01/2023
1	selinexorIBA 01/2023
1	Rituximab (Mabthera)FDA Link 01/2023
1	Immunoglobulin M (IgM)IBA 01/2023
1	Keratin-19 (Keratin 19)IBA 01/2023

Therapy/Procedure

39	Therapeutics 02/2024 - 03/2008
22	Immunotherapy 02/2024 - 01/2018
10	Radiotherapy 02/2024 - 11/2011
6	Drug Therapy (Chemotherapy) 02/2024 - 02/2015
5	Neoadjuvant Therapy 01/2023 - 01/2017
3	Chemoradiotherapy 01/2023 - 09/2022
1	Proton Therapy 02/2024
1	Drug Tapering 07/2023
1	Withholding Treatment 05/2023