Yamini Achari Selected Research

Osteoarthritis

1/2018	Posttraumatic Osteoarthritis Development and Progression in an Ovine Model of Partial Anterior Cruciate Ligament Transection and Effect of Repeated Intra-articular Methylprednisolone Acetate Injections on Early Disease.
12/2015	Single intra-articular dexamethasone injection immediately post-surgery in a rabbit model mitigates early inflammatory responses and post-traumatic osteoarthritis-like alterations.
1/2014	Estrogen receptor beta and truncated variants enhance the expression of transfected MMP-1 promoter constructs in response to specific mechanical loading.
8/2012	Carrageenan-induced transient inflammation in a rabbit knee model: molecular changes consistent with an early osteoarthritis phenotype.
6/2008	Polymorphisms in the promoter regions for human MMP-1 and MMP-13 lead to differential responses to the alpha and beta isoforms of estrogen receptor and their ligand in vitro.
6/2007	Evidence that estrogen receptor beta enhances MMP-13 promoter activity in HIG-82 cells and that this enhancement can be influenced by ligands and involves specific promoter sites.
8/2006	Estrogen receptor alpha regulates matrix metalloproteinase-13 promoter activity primarily through the AP-1 transcriptional regulatory site.

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Yamini Achari Research Topics

Disease

7	Osteoarthritis 01/2018 - 08/2006
7	Inflammation (Inflammations) 03/2017 - 09/2005
2	Joint Diseases (Joint Disease) 01/2014 - 08/2006
2	Cicatrix (Scar) 01/2011 - 09/2005
2	Osteoporosis 06/2008 - 08/2006
1	Anterior Cruciate Ligament Injuries 01/2018
1	Knee Injuries (Knee Injury) 06/2016
1	Necrosis 04/2014
1	Osteophyte 08/2011
1	Wounds and Injuries (Trauma) 01/2011
1	Bone Diseases (Bone Disease) 08/2006

Drug/Important Bio-Agent (IBA)

4	GlucocorticoidsIBA 01/2018 - 09/2005
4	Messenger RNA (mRNA)IBA 08/2015 - 09/2005
2	Methylprednisolone Acetate (Depo-Medrol)FDA LinkGeneric 01/2018 - 03/2017
2	Dexamethasone (Maxidex)FDA LinkGeneric 06/2016 - 12/2015
2	Peptide Hydrolases (Proteases)FDA Link 08/2012 - 08/2006
2	CollagenIBA 01/2011 - 09/2005
2	Estrogens (Estrogen)FDA Link 06/2008 - 08/2006
1	AdipokinesIBA 08/2015
1	CytokinesIBA 08/2015
1	Interleukin-6 (Interleukin 6)IBA 04/2014
1	InterleukinsIBA 04/2014
1	Interleukin-8 (Interleukin 8)IBA 04/2014
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 04/2014
1	Hormones (Hormone)IBA 01/2014
1	CarrageenanIBA 08/2012
1	Biomarkers (Surrogate Marker)IBA 08/2011
1	Matrix Metalloproteinases (MMPs)IBA 08/2011
1	Estrogen ReceptorsIBA 06/2008
1	Matrix Metalloproteinase 13IBA 06/2007
1	BiglycanIBA 09/2005
1	DecorinIBA 09/2005
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 09/2005

Therapy/Procedure

1	Injections 01/2018
1	Intra-Articular Injections 01/2018