[The role of the costo-clavicular compression syndrome within the framework of fibrinolytic therapy of deep arm-vein thrombosis].

Abstract

Eight patients with upper extremity deep-vein thrombosis were treated with thrombolytic agents. The role of a compression syndrome of the costo-clavicular space (found in 5 out of 7 cases) as a probably thrombogenetic factor is discussed. The complications of the therapy were considerable, despite frequent laboratory controls. In one thrombosis of more than 6 months' standing the treatment was ineffective. In the other 7 cases the early clinical results were good. At follow-up 14 to 57 months after thrombolytic therapy, 5 out of 7 cases had residual symptoms (rethrombosis in 2 cases). This may be due to the fact that the compression syndrome was not initially treated, with resultant persistence of the chronic trauma to the vein. Better results can be expected from fibrinolytic therapy in combination with surgical correction of any anatomical narrowing.

• Authors: J Fritschy, A Bollinger, P W Straub
• Journal: Schweizerische medizinische Wochenschrift (Schweiz Med Wochenschr) Vol. 106 Issue 25 Pg. 847-53 (Jun 19 1976) ISSN: 0036-7672 [Print] Switzerland
• Vernacular Title: Zur Rolle des kosto-klavikulären Kompressionssyndroms im Rahmen der fibrinolytischen Therapie tiefer Armvenethrombosen
• PMID: 996502 (Publication Type: English Abstract, Journal Article)

Chemical References

• Coumarins
• Heparin
• Streptokinase
• Urokinase-Type Plasminogen Activator

Topics

• Adult
• Arm (blood supply)
• Coumarins (therapeutic use)
• Female
• Heparin (therapeutic use)
• Humans
• Male
• Middle Aged
• Streptokinase (therapeutic use)
• Syndrome
• Thrombophlebitis (drug therapy, etiology)
• Urokinase-Type Plasminogen Activator (therapeutic use)
• Vascular Diseases (complications)