Abstract |
(1) 6-week-old ICR mice were injected daily with pharmacologic doses of triamcinolone diacetate (1.5 mg/kg body weight) for 8 consecutive weeks. (2) The temporomandibular joint served as a model for histological and histochemical examinations concerning the effect of glucocorticoid hormone upon bone and cartilage. (3) Histochemical reactions indicated a large number of lipid droplets within the peripheral vasculature. (4) Histological examinations revealed pathologic features, indicative of primary osteoarthrosis.
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Authors | M Silbermann |
Journal | Acta anatomica
(Acta Anat (Basel))
Vol. 96
Issue 1
Pg. 9-24
( 1976)
ISSN: 0001-5180 [Print] Switzerland |
PMID | 973542
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Cartilage, Articular
(drug effects, metabolism, pathology)
- Female
- Lipid Metabolism
- Male
- Mandibular Condyle
(drug effects, metabolism, pathology)
- Mice
- Mice, Inbred Strains
- Osteoarthritis
(chemically induced, metabolism, pathology)
- Temporomandibular Joint
(drug effects, metabolism, pathology)
- Triamcinolone
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