Abstract | OBJECTIVE: METHODS: RESULTS: Full remission of the joint inflammation lasting >6 months following injection was achieved in 246 of the 300 injections (82.0%). In 54 (18.0%) of the injected joints, the inflammation recurred within 6 months of injection. In patients with pauciarticular arthritis, 115 of 141 injections (81.6%) resulted in full remission. Discontinuation of all oral medications was accomplished in 43 patients (60.6%) of the total group of 71 patients and in 32 of the 43 patients with pauciarticular disease (74.4%). Correction of joint contraction was achieved in 42 children (55 joints). In all 11 patients with Baker's cyst and in 12 patients with tenosynovitis, complete remission was achieved following injection. No infection or other serious complications occurred in any of the patients following the procedure. CONCLUSION: IA corticosteroid joint injection in children with juvenile arthritis is a safe and effective mode of therapy. It may be the only therapy needed in patients with pauciarticular JRA, obviating the need for prolonged oral medications, and is effective in correcting joint contractions and deformities.
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Authors | S Padeh, J H Passwell |
Journal | Arthritis and rheumatism
(Arthritis Rheum)
Vol. 41
Issue 7
Pg. 1210-4
(Jul 1998)
ISSN: 0004-3591 [Print] United States |
PMID | 9663477
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents
- Triamcinolone Acetonide
- triamcinolone hexacetonide
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Topics |
- Adolescent
- Anti-Inflammatory Agents
(adverse effects, therapeutic use)
- Arthritis
(drug therapy)
- Arthritis, Juvenile
(drug therapy)
- Child
- Child, Preschool
- Chronic Disease
- Female
- Humans
- Infant
- Injections, Intra-Articular
- Male
- Treatment Outcome
- Triamcinolone Acetonide
(adverse effects, analogs & derivatives, therapeutic use)
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