[A trial of the use of the immunocorrective preparation Imunofan for treating diphtheria].

Abstract

Peptide immunocorrector Imunofan was used as adjuvant to conventional treatment. A single intramuscular injection was given daily for 8-10 days (I ml of 0.005% solution). In patients with advanced and toxic diphtheria Imunofan reduced the occurrence of specific complications and lethality fell 4.1-4.8-fold. Imunofan is also recommended for patients with allergic reaction to diphtheria antitoxin.

• Authors: V V Lebedev, V A Bolibok, V V Borzunov, N V Efimov, V Z Tenkachev, V I Pokrovskiĭ
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 68 Issue 2 Pg. 66-8 ( 1996) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Opyt primeneniia immunokorrigiruiushchego preparata "Imunofan" dlia lecheniia difterii.
• PMID: 8771665 (Publication Type: Case Reports, Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Diphtheria Antitoxin
• Oligopeptides
• thymohexin

Topics

• Adjuvants, Immunologic (therapeutic use)
• Adolescent
• Chi-Square Distribution
• Combined Modality Therapy
• Diphtheria (drug therapy)
• Diphtheria Antitoxin (therapeutic use)
• Humans
• Male
• Oligopeptides (therapeutic use)