Abstract | BACKGROUND: OBSERVATIONS:
Trichosporonosis occurs most commonly in neutropenic patients receiving chemotherapy. We describe the second case developing in the acquired immunodeficiency syndrome setting. Cutaneous involvement occurred in approximately 30% of patients and most frequently presented as purpuric papules and nodules with central necrosis or ulceration. Biopsy specimens of these lesions revealed dermal invasion by fungal elements, and culture was positive in greater than 90% of the cases. CONCLUSIONS: Disseminated infection with T beigelii can occur in immunosuppressed patients, including those with acquired immunodeficiency syndrome particularly if associated with neutropenia. Cutaneous involvement is common, presenting as purpuric papules and nodules. Biopsy and culture of cutaneous findings can help establish an accurate diagnosis resulting in rapid and appropriate treatment.
|
Authors | G T Nahass, S P Rosenberg, C L Leonardi, N S Penneys |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 129
Issue 8
Pg. 1020-3
(Aug 1993)
ISSN: 0003-987X [Print] United States |
PMID | 8352606
(Publication Type: Case Reports, Journal Article, Review)
|
Topics |
- AIDS-Related Opportunistic Infections
(complications, microbiology, pathology)
- Adult
- Dermatomycoses
(complications, microbiology, pathology)
- Humans
- Male
- Sarcoma, Kaposi
(etiology)
- Scalp Dermatoses
(complications, microbiology, pathology)
- Trichosporon
|