Isoprinosine: an overview.

Abstract	Isoprinosine appears to have a relatively low degree of both acute and chronic toxicity in both rodent and nonrodent species. Preclinical studies have demonstrated that isoprinosine can inhibit the growth of both DNA and RNA viruses as well as potentiate cell-mediated immune response both in vitro and in vivo. Clinical studies with rhinovirus, herpesvirus, and influenza virus infections in man demonstrated that isoprinosine treatment reduced clinical symptoms and enhanced certain cell-mediated immune responses compared to placebo-treated controls.
Authors	L N Simon, A J Glasky
Journal	Cancer treatment reports (Cancer Treat Rep) Vol. 62 Issue 11 Pg. 1963-9 (Nov 1978) ISSN: 0361-5960 [Print] United States
PMID	83189 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
Chemical References	Inosine Inosine Pranobex
Topics	Animals Clinical Trials as Topic Female Haplorhini Herpes Simplex (drug therapy) Humans In Vitro Techniques Influenza, Human (drug therapy) Inosine (analogs & derivatives) Inosine Pranobex (pharmacology, toxicity) Lymphocyte Activation (drug effects) Male Mice Pregnancy Rats Rhinovirus Virus Diseases (drug therapy, immunology) Virus Replication (drug effects)

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