[Experimental therapy of burn infection caused by pyocyanic bacilli].

Abstract

The chemotherapeutic effect of di-N-quinoxaline oxide derivatives--quinoxidine and diaxidine, as contrasted to that of carbenicillin and hentamycin with their 3- and 10-day application, was studied on a model of a burn in mice infected with Pseudomonas eruginosa. The results achieved by the quinoxidine and dioxidine medication proved much better than those obtained by the use of carbenicillin and hentamycin.

• Authors: A F Girich, V P Iakovlev, E A Rudzit
• Journal: Farmakologiia i toksikologiia (Farmakol Toksikol) 1976 Jan-Feb Vol. 39 Issue 1 Pg. 90-3 ISSN: 0014-8318 [Print] Russia (Federation)
• Vernacular Title: Eksperimental'naia terapiia ozhogovoĭ infektsii, vyzvannoĭ sinegnoĭnoĭ palochkoĭ
• PMID: 815107 (Publication Type: Journal Article)

Chemical References

• Gentamicins
• Quinoxalines
• Carbenicillin

Topics

• Animals
• Carbenicillin (therapeutic use)
• Drug Evaluation, Preclinical
• Gentamicins (therapeutic use)
• Mice
• Pseudomonas Infections (drug therapy, etiology)
• Pseudomonas aeruginosa
• Quinoxalines (therapeutic use)
• Wound Infection (drug therapy)