Effects of fencamfamine withdrawal in rats.

Abstract	1. The effects produced by discontinuation of long-term treatment with fencamfamine (FCF) were evaluated recording behavioral and body weight changes. 2. 48 hr after withdrawal of FCF rats showed a significant decrease in exploratory behavior when compared to saline-treated ones. 3. Discontinuation of treatment with FCF resulted in a significant increase in body weight on days of drug withdrawal. 4. These results suggest that FCF caused signs of withdrawal similar to other psychostimulant drugs.
Authors	C S Planeta, R DeLucia, M L Aizenstein
Journal	General pharmacology (Gen Pharmacol) Vol. 25 Issue 5 Pg. 931-4 (Sep 1994) ISSN: 0306-3623 [Print] England
PMID	7835639 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Central Nervous System Stimulants Norbornanes fencamfamine
Topics	Animals Body Weight (drug effects) Central Nervous System Stimulants (adverse effects) Exploratory Behavior (drug effects) Male Norbornanes (adverse effects) Rats Rats, Wistar Substance Withdrawal Syndrome

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