Lasalocid at the concentration of .0075% (68 g/ton) with and without
roxarsone 45.4 g/ton was fed in combination with the growth promotants
bacitracin methylene disalicylate 200 g/ton,
bambermycins 2 g/ton,
lincomycin 4 g/ton,
nosiheptide 2.5 g/ton,
zinc bacitracin 200 g/ton g/ton, and
virginiamycin 20 g/ton exhibited a high degree of anticoccidial activity against mixed Eimeria
infection in chickens in 9 day challenged battery trials. In these short term challenge trials chicks fed
lasalocid, and the
lasalocid growth promotant combinations, performed significantly better (P < .05) for growth and anticoccidial efficacy than those fed the growth promotants alone, and the infected, unmedicated controls. In almost all instances, the
lasalocid-
roxarsone-
antibiotic combinations allowed for numerical increases in gains, improvement in feed conversion, and numerical decreases in lesions (in some cases, statistically significant (P < .05) over chicks fed
lasalocid alone and/or the
lasalocid antibiotic combination. The growth promotants did not interfere with the anticoccidial activity of
lasalocid. The growth promotants fed alone exhibited no anticoccidial activity. However, when
roxarsone was combined with the
antibiotics, the combination resulted in numerically improved performance, reduced mortality, and in most instances, statistically significant decreases in lesions (P .05) over the infected, unmedicated control.