Fungal retinitis: a case of Torulopsis glabrata infection treated with miconazole.

Abstract

Presumptive embolic chorioretinal Torulopsis glabrata infection is described in a patient who had received prolonged intravenous antibiotic therapy. The ocular findings are compared and contrasted with embolic lesions due to Candida albicans. The patient was treated for 6 weeks with intravenous miconazole. During this time there was shrinkage of the ocular lesions, some improvement in vision and abolition of fungaemia. Improvement in tests of immune function during treatment suggests that an early immunological deficit was secondary to the infection. Intravenous miconazole is a relatively nontoxic alternative to amphotericin and deserves further evaluation in the treatment of ocular mycosis.

• Authors: R B Fitzsimons, M D Nicholls, F A Billson, T I Robertson, P Hersey
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 64 Issue 9 Pg. 672-5 (Sep 1980) ISSN: 0007-1161 [Print] England
• PMID: 7191722 (Publication Type: Case Reports, Journal Article)

Chemical References

• Imidazoles
• Miconazole

Topics

• Adult
• Candida
• Candidiasis (complications)
• Female
• Humans
• Imidazoles (therapeutic use)
• Miconazole (therapeutic use)
• Mycoses (complications, drug therapy, immunology)
• Retinitis (drug therapy)