Effect of parenteral dezocine and placebo in cancer pain.

Abstract

A double-blind, placebo-controlled crossover trial was carried out in 20 hospitalized patients with continuous pain due to cancer to assess the analgesic effectiveness and tolerance of a single intramuscular injection of 10 mg dezocine. Subjective assessments of pain, made at hourly intervals over 4 hours, showed that dezocine produces a statistically significant greater and sustained relief of pain than did placebo. Only minor side-effects were reported.

• Authors: M Staquet
• Journal: Current medical research and opinion (Curr Med Res Opin) Vol. 6 Issue 9 Pg. 634-7 ( 1980) ISSN: 0300-7995 [Print] England
• PMID: 6996934 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Bridged Bicyclo Compounds, Heterocyclic
• Bridged-Ring Compounds
• Cycloparaffins
• Placebos
• Tetrahydronaphthalenes
• dezocine

Topics

• Bridged Bicyclo Compounds, Heterocyclic
• Bridged-Ring Compounds (therapeutic use)
• Clinical Trials as Topic
• Cycloparaffins (therapeutic use)
• Humans
• Neoplasms (complications)
• Pain (drug therapy, etiology)
• Placebos
• Tetrahydronaphthalenes