Experience of three-day trimethoprim therapy for dysuria-frequency in primary health care.

Abstract

Dysuria-frequency in 78 patients was treated for 3 consecutive days with 300 mg trimethoprim administered in a single dose at night. Symptomatic cure was noted in 90% of the patients one week after initiation of therapy. In this investigation a positive urinary culture was found in 74% of the patients and bacteriological cure was obtained in all patients but one. A new infection was registered in 2 patients when controlled one week after the start of therapy. The isolated microorganisms were Escherichia coli in 52% of the cases and Staphylococcus saprophyticus in 29%. The high frequency of the latter offers an explanation to the low reliability of the nitrite dip test in diagnosing significant bacteriuria in this study.

• Authors: J Ahlmén, J Frisén, G Ekbladh
• Journal: Scandinavian journal of infectious diseases (Scand J Infect Dis) Vol. 14 Issue 3 Pg. 213-6 ( 1982) ISSN: 0036-5548 [Print] England
• PMID: 6755659 (Publication Type: Journal Article)

Chemical References

• Trimethoprim

Topics

• Adolescent
• Adult
• Drug Administration Schedule
• Escherichia coli Infections (drug therapy)
• Female
• Humans
• Male
• Middle Aged
• Staphylococcal Infections (drug therapy)
• Trimethoprim (administration & dosage)
• Urinary Tract Infections (drug therapy)
• Urination Disorders (drug therapy)