RNase III is positively regulated by T7 protein kinase.

Abstract

RNase III activity of Escherichia coli is stimulated 4-fold after infection with bacterial virus T7. The mechanism of stimulation is based on phosphate transfer to RNase III by the T7 coded protein kinase. In vitro synthesized protein kinase also stimulates RNase III. Serine is the phosphate acceptor.

• Authors: J E Mayer, M Schweiger
• Journal: The Journal of biological chemistry (J Biol Chem) Vol. 258 Issue 9 Pg. 5340-3 (May 10 1983) ISSN: 0021-9258 [Print] United States
• PMID: 6406499 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Escherichia coli Proteins
• Phosphates
• Serine
• Protein Kinases
• Endoribonucleases
• Ribonuclease III
• ribonuclease III, E coli

Topics

• Endoribonucleases (metabolism)
• Escherichia coli (enzymology)
• Escherichia coli Proteins
• Phosphates (metabolism)
• Protein Kinases (metabolism)
• Ribonuclease III
• Serine (metabolism)
• T-Phages (enzymology)