Abstract | Objective: Design: Systematic literature review/meta-analysis. Methods: We searched PubMed, Cumulative Index to Nursing and Allied Health, EMBASE, Cochrane Central Register of Controlled Trials, Scopus, and Web of Science from December 1, 2019, to June 2, 2023, for studies evaluating the COVID-19 vaccine effectiveness (VE) against post-COVID conditions among fully vaccinated individuals who received two doses of COVID-19 vaccine. A post-COVID condition was defined as any symptom that was present four or more weeks after COVID-19 infection. We calculated the pooled diagnostic odds ratio (DOR) (95% confidence interval) for post-COVID conditions between fully vaccinated and unvaccinated individuals. Vaccine effectiveness was estimated as 100% x (1-DOR). Results: Conclusions: Receiving a complete COVID-19 vaccination prior to contracting the virus resulted in a significant reduction in post-COVID conditions throughout the study period, including during the Omicron era. Vaccine effectiveness demonstrated an increase when supplementary doses were administered.
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Authors | Alexandre R Marra, Takaaki Kobayashi, Gustavo Yano Callado, Isabele Pardo, Maria Celidonio Gutfreund, Mariana Kim Hsieh, Vivian Lin, Mohammed Alsuhaibani, Shinya Hasegawa, Joseph Tholany, Eli N Perencevich, Jorge L Salinas, Michael B Edmond, Luiz Vicente Rizzo |
Journal | Antimicrobial stewardship & healthcare epidemiology : ASHE
(Antimicrob Steward Healthc Epidemiol)
Vol. 3
Issue 1
Pg. e168
( 2023)
ISSN: 2732-494X [Electronic] England |
PMID | 38028898
(Publication Type: Journal Article)
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Copyright | © The Author(s) 2023. |