At the time of the spread of the
COVID-19 epidemic, blurred lung signs suggested by imaging examination are particularly common. Novel
coronavirus infection is mainly caused by respiratory symptoms. In the early stage of imaging examination, multiple small patchy shadows or ground glass shadows and invasive shadows of both lungs are dominant. While the pulmonary involvement in
Crohn's disease (CD) is rare and not widely reported. For CD patients, the pulmonary manifestations do not belong to its routine symptoms. The lung involvement of CD patients is difficult to attract clinicians' attention. If CD patients have vague lung manifestations but have no response to routine treatment, they should consider the
respiratory diseases related to CD. We describe a rare case of granulomatous
inflammation associated with
Crohn's disease. The patient do not respond to conventional treatment. The final treatment plan was CD
immunomodulatory therapy (oral
corticosteroids and
azathioprine).
After treatment, a review of the lung CT showed focal
fibrosis and significant improvement in the lung lesions. It suggests that CD related
respiratory diseases should be considered when CD patients have abnormal lung manifestations that do not respond to conventional treatment.