Diabulimia: A Risky Trend Among Adults with Type 1 Diabetes Mellitus.

Abstract

OBJECTIVE:

Poor adherence leads to worse glycemic control and increased complications in patients with type 1 diabetes mellitus (T1DM). Diabulimia characterizes patients with T1DM who skip or use less insulin for weight loss purposes. The study objectives were to determine: (1) the prevalence of diabulimia among adult patients with T1DM, (2) compare patients with and without diabulimia, and (3) identify factors that may place individuals at higher risk of diabulimia.

METHODS:

A 40-item, web-based survey was administered to 21 T1DM discussion boards, Listservs, and social media outlets. The survey assessed demographics, diabetes management, psychiatric diagnoses, and screened for diabulimia. Individuals who reported intentionally skipping or using less insulin than directed for the purpose of weight loss or to prevent weight gain in the past 12 months were classified as having diabulimia.

RESULTS:

Of the 225 participants who completed the survey, 8.9% had diabulimia. Patients with diabulimia had elevated hemoglobin A1C (A1C) levels (8.4% vs 6.9%; P = .014), higher rates of a diabetes-related emergency department visits or hospitalization (30.0% vs 13.2%; P = .042), and higher rates of a major depressive disorder diagnosis (40.0% vs 11.5%; P < .001) than patients without diabulimia. Factors associated with diabulimia included high A1C levels (odds ratio, 1.43; 95% CI [1.08-1.91]; P = .014) and a major depressive disorder diagnosis (odds ratio, 4.87; 95% CI [1.31-18.22]; P = .018).

CONCLUSION:

Approximately 1 in 11 adult patients with T1DM screened positive for diabulimia. Higher A1C levels and a diagnosis of major depressive disorder were associated with diabulimia.

• Authors: Eric J Ip, Shadi Doroudgar, Aava Salehi, Fojan Salehi, Mitra Najmi
• Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists (Endocr Pract) Vol. 29 Issue 11 Pg. 849-854 (Nov 2023) ISSN: 1530-891X [Print] United States
• PMID: 37567472 (Publication Type: Journal Article)
• Copyright: Copyright © 2023 AACE. Published by Elsevier Inc. All rights reserved.

Chemical References

• Glycated Hemoglobin
• Insulin
• Insulin, Regular, Human

Topics

• Humans
• Adult
• Diabetes Mellitus, Type 1 (complications, epidemiology)
• Diabulimia (complications)
• Glycated Hemoglobin
• Depressive Disorder, Major (complications)
• Feeding and Eating Disorders (complications)
• Insulin
• Weight Loss
• Insulin, Regular, Human