Abstract | Introduction: Materials and Methods: Results: There was a direct relationship between the luminal subtype carcinoma and higher GATA-3 expression (P-value: 0.001) and between triple-negative carcinoma and lower GATA-3 expression (P-value: 0.001). Moreover, there was a direct relationship between the metastasis rate and the tumor's grade with GATA-3 staining (P-value: 0.000 and 0.001, respectively). Conclusion: GATA-3 expression is related to the histopathologic and prognostic factors. GATA3 can be introduced as an important predictor in breast cancer patients.
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Authors | Hedieh M Tabriz, Elahe Farmani, Elham Nazar, Arezoo E Javadi |
Journal | Indian journal of pathology & microbiology
(Indian J Pathol Microbiol)
2023 Apr-Jun
Vol. 66
Issue 2
Pg. 286-290
ISSN: 0974-5130 [Electronic] India |
PMID | 37077069
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers, Tumor
- GATA3 Transcription Factor
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Topics |
- Humans
- Female
- Breast Neoplasms
(diagnosis, genetics, metabolism)
- Prognosis
- Biomarkers, Tumor
(genetics, metabolism)
- GATA3 Transcription Factor
(genetics)
- Iran
- Mastectomy
- Carcinoma
(pathology)
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