Progression of human monkeypox infection despite tecovirimat in an immunocompromised adult.

Abstract

We report a case of an immunocompromised man with monkeypox who experienced disease progression despite timely initiation of tecovirimat and ultimately required utilization of cidofovir and VIGIV for treatment. In immunocompromised patients, monkeypox might present with a more severe course of disease requiring consideration of alternative treatment strategies.

• Authors: Fabian Dammann, Mohammed Raja, Jose F Camargo
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 25 Issue 1 Pg. e14022 (Feb 2023) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 36714983 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2023 Wiley Periodicals LLC.

Chemical References

• Antiviral Agents
• human intravenous vaccinia immune globulin
• Benzamides

Topics

• Male
• Humans
• Adult
• Mpox (monkeypox) (drug therapy)
• Antiviral Agents (therapeutic use)
• Benzamides (therapeutic use)
• Immunocompromised Host