The Positive Impact of a Chemotherapeutic Approach on Relapse Ependymoma or WHO Grade III Anaplastic Ependymoma: Report of a Rare Case.

Abstract

Children with recurrent ependymoma have a poor prognosis. Reirradiation has been proposed as an effective treatment for relapsed ependymoma. In this report, we present the case of a 14-year-old male child with a World Health Organization (WHO) grade III relapse ependymoma, emphasizing the imaging feature that helps differentiate the relapse ependymoma, which is a rarer condition in children. Being able to determine this tumor by its imaging appearance is important to risk stratify patient management decisions. The survival rate of ependymoma is usually five years, but in this case, we present a 14-year-old male child alive with reirradiation and chemotherapy management. The prognosis of the patient after undergoing treatment was good.

• Authors: Abhyuday Meghe, Mayur B Wanjari, Gajanan N Umalkar, Ranjana Sharma
• Journal: Cureus (Cureus) Vol. 14 Issue 12 Pg. e32534 (Dec 2022) ISSN: 2168-8184 [Print] United States
• PMID: 36654551 (Publication Type: Case Reports)
• Copyright: Copyright © 2022, Meghe et al.