Abstract | BACKGROUND: OBJECTIVE: STUDY DESIGN: Prospective study. SETTING: Department of Anesthesiology and Pain Medicine, Neurosurgery at Daegu Wooridul Spine Hospital. METHODS: Sixty-three patients were randomized into 2 LESI groups: one received 4 mg of dexamethasone (n = 25) and the other received 8 mg of dexamethasone (n = 28). Visual analog scale (VAS) scores and the Oswestry Disability Index (ODI) were determined. In addition, serum cortisol and glucose concentrations were measured before treatment, at the second LESI (one month follow-up), and at 2 months. All patients received LESI. RESULTS:
Blood glucose and serum cortisol concentrations were not significantly different within a group and between groups. There was no difference in serum cortisol and glucose levels, VAS, and ODI between the first LESI and second LESI in both groups. The VAS and ODI were reduced in both groups and the difference between groups was not statistically significant. LIMITATIONS: The dexamethasone dosage was not variable; hence, we could not use larger doses of dexamethasone. Secondly, the blood draw interval was longer in this study than in previous studies. CONCLUSION:
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Authors | Chan Hong Park, Yho Han Jang, Sang Ho Lee |
Journal | Pain physician
(Pain Physician)
Vol. 25
Issue 7
Pg. E1081-E1085
(10 2022)
ISSN: 2150-1149 [Electronic] United States |
PMID | 36288594
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Adrenocorticotropic Hormone
- Blood Glucose
- Dexamethasone
- Hydrocortisone
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Topics |
- Humans
- Adrenocorticotropic Hormone
- Blood Glucose
- Dexamethasone
(therapeutic use)
- Hydrocortisone
- Injections, Epidural
(methods)
- Low Back Pain
(drug therapy)
- Lumbar Vertebrae
(surgery)
- Prospective Studies
- Treatment Outcome
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