Abstract | BACKGROUND: Capnocytophaga canimorsus, a Gram-negative rod, belongs to the Flavobacteriaceae family and colonizes the oropharynx of dogs and cats. Infections with C. canimorsus are rare and can induce a systemic infection with a severe course of the disease. So far, only five case reports of C. canimorsus infections associated with Waterhouse-Friderichsen Syndrome (WFS) have been reported with only two of the patients having a history of splenectomy. CASE PRESENTATION: CONCLUSIONS: The occurrence of a severe sepsis after dog bite should always urge the attending physician to consider C. canimorsus as the disease-causing pathogen. A therapeutic regimen covering C. canimorsus such as aminopenicillins or carbapenems should be chosen. However, despite maximum therapy, the prognosis of C. canimorsus-induced septic shock remains very poor. Asplenic or otherwise immunocompromised patients are at higher risk for a severe course of disease and should avoid exposure to dogs and cats and consider antibiotic prophylaxis after animal bite.
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Authors | Franziska Schuler, Jan-Sören Padberg, Carsten Hullermann, Philipp Kümpers, Johannes Lepper, Miriam Schulte, Andreas Uekötter, Frieder Schaumburg, Barbara C Kahl |
Journal | BMC infectious diseases
(BMC Infect Dis)
Vol. 22
Issue 1
Pg. 696
(Aug 17 2022)
ISSN: 1471-2334 [Electronic] England |
PMID | 35978295
(Publication Type: Case Reports, Journal Article)
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Copyright | © 2022. The Author(s). |
Topics |
- Animals
- Bites and Stings
(complications)
- Capnocytophaga
- Cat Diseases
- Cats
- Dog Diseases
(diagnosis, therapy)
- Dogs
- Female
- Gram-Negative Bacterial Infections
(microbiology)
- Sepsis
(diagnosis)
- Waterhouse-Friderichsen Syndrome
(complications)
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